SASBDB entries for UniProt ID: Q99572

SASDPE4 – P2X7 ballast domain

UniProt ID: Q99572 (395-595) P2X purinoceptor 7
P2X purinoceptor 7 experimental SAS data
P2X purinoceptor 7 Kratky plot
Sample: P2X purinoceptor 7 trimer, 74 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7.5, 150 mM NaCl, 5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Jun 4
New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain. J Biol Chem :102495 (2022)
Sander S, Müller I, Alai MG, Nicke A, Tidow H
RgGuinier 3.1 nm
Dmax 10.5 nm
VolumePorod 94 nm3

SASDPF4 – P2X7 ballast domain in complex with Ca2+-calmodulin

UniProt ID: P0DP23 (1-149) Calmodulin-1

UniProt ID: Q99572 (395-595) P2X purinoceptor 7
Calmodulin-1P2X purinoceptor 7 experimental SAS data
Calmodulin-1 P2X purinoceptor 7 Kratky plot
Sample: Calmodulin-1 monomer, 17 kDa Homo sapiens protein
P2X purinoceptor 7 monomer, 25 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7.5, 150 mM NaCl, 5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Jun 4
New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain. J Biol Chem :102495 (2022)
Sander S, Müller I, Alai MG, Nicke A, Tidow H
RgGuinier 3.2 nm
Dmax 13.5 nm
VolumePorod 73 nm3