SASDVC8 – Hendra virus protein P/V/W PNT3 domain

Protein W experimental SAS data
Hendra virus protein P/V/W PNT3 domain Rg histogram
Sample: Protein W monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
Gondelaud F, Leval J, Arora L, Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.4 nm
Dmax 13.5 nm
VolumePorod 42 nm3

SASDVD8 – Hendra virus protein P/V/W PNT3 low-K domain

Protein W (artificial PNT3 variant - low-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 low-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - low-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
Gondelaud F, Leval J, Arora L, Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.8 nm
Dmax 18.0 nm
VolumePorod 48 nm3

SASDVE8 – Hendra virus protein P/V/W PNT3 high-K domain

Protein W (artificial PNT3 variant - high-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 high-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - high-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Apr 5
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
Gondelaud F, Leval J, Arora L, Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.1 nm
Dmax 14.7 nm
VolumePorod 54 nm3

SASDSP8 – RNA Device 43 in ligand-free state (apo-D43)

RNA Device 43 in ligand-free state experimental SAS data
OTHER model
Sample: RNA Device 43 in ligand-free state monomer, 40 kDa synthetic construct RNA
Buffer: 10 mM Bis-Tris, 100 mM KCl, and 1 mM MgCl2, pH: 6.8
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 25
Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells. Nucleic Acids Res 53(5) (2025)
Stagno JR, Deme JC, Dwivedi V, Lee YT, Lee HK, Yu P, Chen SY, Fan L, Degenhardt MFS, Chari R, Young HA, Lea SM, Wang YX
RgGuinier 3.4 nm
Dmax 12.2 nm
VolumePorod 58 nm3

SASDSQ8 – RNA Device 43 in ligand-bound state (holo-D43)

RNA Device 43 in ligand-bound state experimental SAS data
OTHER model
Sample: RNA Device 43 in ligand-bound state monomer, 40 kDa synthetic construct RNA
Buffer: 10 mM Bis-Tris, 100 mM KCl, and 1 mM MgCl2, pH: 6.8
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 25
Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells. Nucleic Acids Res 53(5) (2025)
Stagno JR, Deme JC, Dwivedi V, Lee YT, Lee HK, Yu P, Chen SY, Fan L, Degenhardt MFS, Chari R, Young HA, Lea SM, Wang YX
RgGuinier 3.3 nm
Dmax 12.1 nm
VolumePorod 56 nm3

SASDVX3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM CaCl2, 0.5 mM deuterated n-Dodecyl-B-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.1 nm
Dmax 17.1 nm
VolumePorod 581 nm3

SASDVY3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM EDTA, 0.5 mM deuterated n-Dodecyl-β-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.2 nm
Dmax 18.4 nm
VolumePorod 558 nm3

SASDWF4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS224

Outer membrane protein MIP(2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide experimental SAS data
SREFLEX model
Sample: Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein
(2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide monomer, 1 kDa
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem (2025)
Pérez Carrillo VH, Whittaker JJ, Wiedemann C, Harder JM, Lohr T, Jamithireddy AK, Dajka M, Goretzki B, Joseph B, Guskov A, Harmer NJ, Holzgrabe U, Hellmich UA
RgGuinier 2.9 nm
Dmax 9.7 nm
VolumePorod 61 nm3

SASDWG4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS227

Outer membrane protein MIP(2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide experimental SAS data
SREFLEX model
Sample: Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein
(2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide monomer, 1 kDa
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem (2025)
Pérez Carrillo VH, Whittaker JJ, Wiedemann C, Harder JM, Lohr T, Jamithireddy AK, Dajka M, Goretzki B, Joseph B, Guskov A, Harmer NJ, Holzgrabe U, Hellmich UA
RgGuinier 3.0 nm
Dmax 10.0 nm
VolumePorod 65 nm3

SASDVK4 – Immunoglobulin light chain AL55

Immunoglobulin light chain AL55 experimental SAS data
SWISSMODEL model
Sample: Immunoglobulin light chain AL55 dimer, 47 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2022 Jan 15
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 61 nm3

4690 hits found.