Small Angle Scattering Biological Data Bank SASBDB

SASDLT5 – Modification methylase SsoII (M.SsoII) protein bound to 12-bp DNA

Modification methylase SsoII12-bp DNA experimental SAS data

Modification methylase SsoII (M.SsoII) protein bound to 12-bp DNA Rg histogram

Sample:	Modification methylase SsoII monomer, 43 kDa Shigella sonnei protein 12-bp DNA monomer, 8 kDa DNA
Buffer:	50 mM Na-phosphate buffer, pH: 7
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2007 Mar 13

Flexibility of the linker between the domains of DNA methyltransferase SsoII revealed by small-angle X-ray scattering: implications for transcription regulation in SsoII restriction-modification syste... PLoS One 9(4):e93453 (2014)
Konarev PV, Kachalova GS, Ryazanova AY, Kubareva EA, Karyagina AS, Bartunik HD, Svergun DI

R_g^Guinier	2.8	nm
D_max	11.0	nm
Volume^Porod	85	nm³

SASDB35 – Staphylococcus aureus thiaminase II

Thiaminase type II enzyme experimental SAS data

Sample:	Thiaminase type II enzyme tetramer, 107 kDa Staphylococcus aureus protein
Buffer:	100 mM Tris-HCl, pH: 7.5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2011 May 11

Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases. Acta Crystallogr D Biol Crystallogr 69(Pt 12):2320-9 (2013)
Begum A, Drebes J, Kikhney A, Müller IB, Perbandt M, Svergun D, Wrenger C, Betzel C

R_g^Guinier	3.4	nm
D_max	11.0	nm
Volume^Porod	168	nm³

SASDMU2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) without Dox

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) without Dox experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) without Dox monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study. Biomacromolecules 14(11):4061-70 (2013)
Filippov SK, Franklin JM, Konarev PV, Chytil P, Etrych T, Bogomolova A, Dyakonova M, Papadakis CM, Radulescu A, Ulbrich K, Stepanek P, Svergun DI

R_g^Guinier	6.1	nm
D_max	20.5	nm

SASDMV2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) with Dox

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) with Dox (10%) experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - 5α-cholestan-3-one) with Dox (10%) monomer, 220 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	7.5	nm
D_max	25.5	nm

SASDMW2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) without Dox

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) without Dox experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) without Dox monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	6.4	nm
D_max	22.5	nm

SASDMX2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) with Dox (10%)

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) with Dox (10%) experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Opb-Chol) with Dox (10%) monomer, 225 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	10.0	nm
D_max	21.9	nm

SASDMY2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) without Dox

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) without Dox experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) without Dox monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	6.5	nm
D_max	22.9	nm

SASDMZ2 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) with Dox (10%)

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) with Dox (10%) experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - Lev-Chol) with Dox (10%) monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	6.9	nm
D_max	23.8	nm

SASDM23 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) without Dox

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) without Dox experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) without Dox monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 16

R_g^Guinier	5.9	nm
D_max	19.7	nm

SASDM33 – Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) with Dox (10%)

Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) with Dox (10%) experimental SAS data

Sample:	Hydrolytically Degradable Polymer Micelles for Drug Delivery (structure of hydrophobic substituent - cholest-4-en-3-one) with Dox (10%) monomer, 125 kDa
Buffer:	phosphate buffer saline (PBS) (pH 5.0), pH: 5
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2012 Aug 19

R_g^Guinier	5.5	nm
D_max	18.3	nm

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