NMR structure of emfourin, a novel protein metalloprotease inhibitor: insights into the mechanism of action.

Bozin T, Berdyshev I, Chukhontseva K, Karaseva M, Konarev P, Varizhuk A, Lesovoy D, Arseniev A, Kostrov S, Bocharov E, Demidyuk I
J Biol Chem :104585 (2023 Mar 6)

PMID: 36889586 doi: 10.1016/j.jbc.2023.104585

Submitted to SASBDB: 2020 Feb 26 Published in SASBDB: 2023 Mar 10

SASDHN7 – Emfourin (M4in) from Serratia proteamaculans, M4 family peptidase inhibitor Sample: Emfourin (Protealysin-associated protein) monomer, 13 kDa Serratia proteamaculans protein Buffer: 50 mM Tris-HCL, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Apr 22 RgGuinier 1.7 nm Dmax 5.5 nm VolumePorod 16 nm3