Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C
Science Advances 7(10):eabf1004 (2021 Mar 03)

doi: 10.1126/sciadv.abf1004
Submitted to SASBDB: 2020 Dec 9
Published in SASBDB:

SASDKJ4 – SARS-CoV-2 nsp7 and nsp8

Replicase polyprotein 1a - nsp7Replicase polyprotein 1a - nsp8 experimental SAS data
PDB model
Sample: Replicase polyprotein 1a - nsp7, 18 kDa Severe acute respiratory … protein
Replicase polyprotein 1a - nsp8, 44 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, pH 8.0, 100 mM NaCl, 4 mM DTT, 4 mM MgCl2, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 19
RgGuinier 3.4 nm
Dmax 13.5 nm
VolumePorod 92 nm3