Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro.

Redecke L, von Bergen M, Clos J, Konarev PV, Svergun DI, Fittschen UE, Broekaert JA, Bruns O, Georgieva D, Mandelkow E, Genov N, Betzel C
J Struct Biol 157(2):308-20 (2007 Feb)
PMID: 17023178
doi: 10.1016/j.jsb.2006.06.013
Submitted to SASBDB: 2021 Aug 18
Published in SASBDB:

SASDMA7 – Prion protein aggregate in solution

Major prion protein experimental SAS data
DAMMIN model
Sample: Major prion protein 24-mer, 664 kDa Homo sapiens protein
Buffer: 5 mM sodium acetate, pH: 5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2005 Jun 2
RgGuinier 9.8 nm
Dmax 32.0 nm
VolumePorod 3320 nm3