Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme.

Bezem MT, Baumann A, Skjærven L, Meyer R, Kursula P, Martinez A, Flydal MI
Sci Rep 6:30390 (2016 Jul 27)
PMID: 27462005
doi: 10.1038/srep30390 		Submitted to SASBDB: 2016 Jun 25
Published in SASBDB:

SASDBZ4 – Tyrosine hydroxylase (Isoform 1, Homo sapiens)

Tyrosine hydroxylase, isoform 1 experimental SAS data
BUNCH model
Sample: Tyrosine hydroxylase, isoform 1 tetramer, 222 kDa Homo sapiens protein
Buffer: 20 mM Na-HEPES 200 mM NaCl, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Jun 14
RgGuinier 4.7 nm
Dmax 20.0 nm
VolumePorod 520 nm3