Structural and functional repurposing of picornaviral H-box 2A proteins

Marion Pichon

Submitted to SASBDB: 2024 Apr 30 Published in SASBDB: 2026 Apr 30

SASDUY7 – Aichivirus A 2A protein at neutral pH Sample: Genome polyprotein monomer, 15 kDa Aichi virus (strain … protein Buffer: 20 mM HEPES,150 mM NaCl, 2 mM TCEP, 1% v/v glycerol, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 11 RgGuinier 1.8 nm Dmax 7.4 nm VolumePorod 18 nm3

SASDUZ7 – Human Parechovirus 1 2A protein dimer at neutral pH Sample: Genome polyprotein (I918M) dimer, 34 kDa Human parechovirus 1 … protein Buffer: 20 mM HEPES,150 mM NaCl, 2 mM TCEP, 1% v/v glycerol, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 11 RgGuinier 2.2 nm Dmax 8.0 nm VolumePorod 58 nm3

SASDU28 – Phospholipase A and acyltransferase 3 at neutral pH Sample: Phospholipase A and acyltransferase 3 monomer, 15 kDa Homo sapiens protein Buffer: 20 mM HEPES,150 mM NaCl, 2 mM TCEP, 1% v/v glycerol, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 11 RgGuinier 1.6 nm Dmax 5.5 nm VolumePorod 22 nm3