A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design

Papadopoulos A, Anlauf M, Reiners J, Paik S, Krüger A, Lückel B, Bott M, Drepper T, Frunzke J, Gohlke H, Weidtkamp-Peters S, Smits S, Gertzen C
ACS Sensors (2026 Jan 11)

doi: 10.1021/acssensors.5c02481

Submitted to SASBDB: 2025 Feb 26 Published in SASBDB: 2025 Dec 11

SASDWP9 – Ratiometric matryoshka biosensor for Fe2+ – MDtxRGA_G149 Sample: Ratiometric matryoshka biosensor for Fe2+ monomer, 84 kDa synthetic construct protein Buffer: 20 mM MOPS, 250 mM KCl,, pH: 7 Experiment: SAXS data collected at BM29, ESRF on 2024 Nov 15 RgGuinier 3.6 nm Dmax 12.4 nm VolumePorod 118 nm3