Clocked stepping of an artificial protein walker along a DNA track.

Nilsson P, Robertson NO, Gustafsson N, Davies RB, Liew CW, Lyons A, Eichhorn R, Niman CS, Blab GA, Bromley EHC, Whitten AE, Duff AP, Unksov IN, Beech JP, Jönsson P, Böcking T, Höcker B, Woolfson DN, Forde NR, Linke H, Curmi PMG
Nat Nanotechnol (2026 Jul 6)
PMID: 42410215
doi: 10.1038/s41565-026-02211-3 		Submitted to SASBDB: 2025 Feb 20
Published in SASBDB:

SASDWM8 – Tumbleweed protein composed of synthetic constructs TW1 and TW2 linked covalently via SpyTag/SpyCatcher

Tumbleweed experimental SAS data
MULTIFOXS model
Sample: Tumbleweed monomer, 133 kDa synthetic construct protein
Buffer: 10 mM HEPES, 150 mM NaCl, 5mM MgCl2, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2023 Mar 15
RgGuinier 6.7 nm
Dmax 27.0 nm
VolumePorod 190 nm3