Integrative Structural Characterization of Candida glabrata Phosphoglycerate Kinase by Small-Angle X-ray Scattering and AlphaFold: Implications for Therapeutic Targeting in Candidiasis

Cuéllar-Cruz M, Maqueda Cabrera E, Siliqi D, Moreno A
ACS Omega (2026 Jan 21)

doi: 10.1021/acsomega.5c11751 		Submitted to SASBDB: 2025 Mar 13
Published in SASBDB:

SASDXB2 – Phosphoglycerate kinase

Phosphoglycerate kinase experimental SAS data
ALPHAFOLD model
Sample: Phosphoglycerate kinase monomer, 45 kDa Nakaseomyces glabratus protein
Buffer: 50 mM sodium phosphate, 500 mM NaCl, 500 mM imidazole, 1 mM phenylmethylsulfonyl fluoride (PMSF), pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2025 Feb 13
RgGuinier 2.9 nm
Dmax 10.3 nm
VolumePorod 79 nm3