In vitro characterization of the catalytic domain of human histone deacetylase 5

Mammen C, Hornung F, Anzenhofer C, Schumacher J, Reiners J, Li J, Mazzone F, Bilsing F, Kassack M, Kurz T, Smits S
Scientific Reports (2026 Feb 27)

doi: 10.1038/s41598-026-37633-5 		Submitted to SASBDB: 2025 Jul 21
Published in SASBDB:

SASDXL6 – Histone deacetylase 5 (HDAC5)

Histone deacetylase 5 experimental SAS data
Histone deacetylase 5 Kratky plot
Sample: Histone deacetylase 5 monomer, 51 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM KCl, 1 mM DTT,, pH: 7.5
Experiment: SAXS data collected at Xenocs Xeuss 2.0 Q-Xoom, Center for Structural Studies, Heinrich-Heine-University on 2024 Feb 29
RgGuinier 2.8 nm
Dmax 10.1 nm
VolumePorod 82 nm3