Structures of nucleotide-bound Redondovirus Rep protein link conformation and function.

Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
PLoS Pathog 22(3):e1013997 (2026 Mar)
PMID: 41779823
doi: 10.1371/journal.ppat.1013997 		Submitted to SASBDB: 2025 Aug 11
Published in SASBDB:

SASDXP7 – Human lung-associated vientovirus FB Replication-Associated Protein Apo form (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
RgGuinier 5.2 nm
Dmax 155.0 nm

SASDXQ7 – Human lung-associated vientovirus FB Replication-Associated Protein Apo form (Rep) Hexamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Hexamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Hexamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Hexamer hexamer, 243670 kDa Vitentovirus RB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
RgGuinier 4.7 nm
Dmax 144.0 nm
VolumePorod 488 nm3

SASDXR7 – Human lung-associated vientovirus FB Replication-Associated Protein ATP-bound (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
RgGuinier 5.5 nm
Dmax 162.0 nm
VolumePorod 668 nm3

SASDXS7 – Human lung-associated vientovirus FB Replication-Associated Protein ADP-bound (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
RgGuinier 5.5 nm
Dmax 239.0 nm
VolumePorod 850 nm3

SASDXT7 – Human lung-associated vientovirus FB Replication-Associated Protein ADP-bound (Rep) Hexamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Hexamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Hexamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Hexamer hexamer, 243670 kDa Vitentovirus RB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
RgGuinier 4.9 nm
Dmax 162.0 nm
VolumePorod 487 nm3