Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition.

Mazzoletti D, Garavaglia A, Fisher H, Gao N, Morrone C, Olinares PDB, Chait BT, Jeruzalmi D, Miggiano R
Protein Sci 35(9):e70771 (2026 Sep)
PMID: 42635293
doi: 10.1002/pro.70771 		Submitted to SASBDB: 2025 Nov 27
Published in SASBDB:

SASDYU2 – DNA replication protein DciA from M.turberculosis

DNA replication protein DciA experimental SAS data
OTHER model
Sample: DNA replication protein DciA monomer, 21 kDa Mycobacterium tuberculosis protein
Buffer: 20 mM HEPES, 300 mM NaCl, 2mM b-Me, 5% glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2025 Oct 31
RgGuinier 3.2 nm
Dmax 14.1 nm
VolumePorod 36 nm3