Insights into the Solution Structure and Oligomeric State of Fructose-1,6-bisphosphate Aldolase and Pyruvate Kinase from Nakaseomyces glabratus by Small-Angle X-ray Scattering (SAXS) and AlphaFold Prediction

Cuéllar-Cruz M, Siliqi D, Moreno A
ACS Omega (2026 Sep 03)

doi: 10.1021/acsomega.6c06099 		Submitted to SASBDB: 2026 Feb 11
Published in SASBDB:

SASDYV6 – Candida glabrata Pyruvate Kinase (Pk)

Pyruvate Kinase experimental SAS data
GASBOR model
Sample: Pyruvate Kinase monomer, 55 kDa Nakaseomyces glabratus protein
Buffer: 20 mM Tris-HCl pH, 300 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2025 Sep 10
RgGuinier 4.0 nm
Dmax 17.3 nm
VolumePorod 88 nm3

SASDYW6 – Candida glabrata Fructose Bisphosphate Aldolase (Fba1)

Fructose Biphosphate Aldolase experimental SAS data
GASBOR model
Sample: Fructose Biphosphate Aldolase dimer, 74 kDa Nakaseomyces glabratus protein
Buffer: 20 mM Tris-HCl pH, 300 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2025 Dec 10
RgGuinier 4.9 nm
Dmax 12.7 nm
VolumePorod 167 nm3