Structure of the HIV-1 Gag polyprotein in solution.

Shtykova EV, Petoukhov MV, Dadinova LA, Denieva ZG, Batishchev OV
J Struct Biol 218(4):108372 (2026 Sep 13)

PMID: 42732856 doi: 10.1016/j.jsb.2026.108372

Submitted to SASBDB: 2026 Aug 5 Published in SASBDB: 2026 Sep 18

SASD2H3 – Human immunodeficiency virus type 1 (HIV-1) Gag Polyprotein at 8mg/ml Sample: Gag polyprotein trimer, 150 kDa Human immunodeficiency virus … protein Buffer: 20 mM Tris, 500 mM NaCl, 1 mM phenylmethylsulfonyl fluoride, 10 mM beta-mercaproethanol, 1 µM ZnCl2, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Jun 24 RgGuinier 4.8 nm Dmax 18.0 nm VolumePorod 202 nm3

SASD2E6 – Human immunodeficiency virus type 1 (HIV-1) Gag Polyprotein at 2 mg/ml Sample: Gag polyprotein monomer, 50 kDa Human immunodeficiency virus … protein Buffer: 20 mM Tris, 500 mM NaCl, 1 mM phenylmethylsulfonyl fluoride, 10 mM beta-mercaproethanol, 1 µM ZnCl2, pH: 7.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Jun 24 RgGuinier 4.1 nm Dmax 16.0 nm VolumePorod 64 nm3