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4 hits found for Vishwakarma

SASDPE3 – GST-Endonuclease 8 2/Single-stranded DNA-binding protein (Nei2-SSB) complex

Endonuclease 8 2Single-stranded DNA-binding protein experimental SAS data
DAMMIF model
Sample: Endonuclease 8 2 dimer, 108 kDa Mycobacterium tuberculosis (strain … protein
Single-stranded DNA-binding protein octamer, 139 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2019 Jul 10
Identification and characterization of MtbNei2-SSB forms novel pre-replicative BER complex in Mycobacterium tuberculosis.
Jyoti Vishwakarma
RgGuinier 5.5 nm
Dmax 21.0 nm
VolumePorod 734 nm3

SASDPJ4 – N-terminal domain of EccA5

ESX-5 secretion system protein EccA5 experimental SAS data
DAMMIF model
Sample: ESX-5 secretion system protein EccA5 monomer, 31 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2018 Mar 9
The crystal structure of the TPR domain of the EccA5 ATPase and demonstration of its interaction with EspG5 from the mycobacterial ESX-5 pathway. FEBS Lett (2026)
...Vishwakarma J, Kabrambam R, Kumar S, Ramachandran R
RgGuinier 2.6 nm
Dmax 7.8 nm
VolumePorod 57 nm3

SASDWE7 – EccA5-N terminal domain and EspG5 complex of Mycobacterium tuberculosis

ESX-5 secretion-associated protein EspG5ESX-5 secretion system protein EccA5 experimental SAS data
DAMFILT model
Sample: ESX-5 secretion-associated protein EspG5 monomer, 32 kDa Mycobacterium tuberculosis (strain … protein
ESX-5 secretion system protein EccA5 monomer, 31 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50 mM HEPES, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2025 Jan 28
The crystal structure of the TPR domain of the EccA5 ATPase and demonstration of its interaction with EspG5 from the mycobacterial ESX-5 pathway. FEBS Lett (2026)
...Vishwakarma J, Kabrambam R, Kumar S, Ramachandran R
RgGuinier 3.5 nm
Dmax 9.1 nm
VolumePorod 83 nm3

SASDKU9 – Thymidylate kinase (dTMP kinase) at pH 8.0

dTMP kinase experimental SAS data
GASBOR model
Sample: dTMP kinase dimer, 57 kDa Brugia malayi protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2018 Oct 7
Crystal Structure of the Brugia malayi Thymidylate Kinase-dTMP Complex and Small Angle X-ray Scattering Experiments Identifies Changes in the Dimeric Association Compared to the Human Homolog Crystallography Reports 68(7):1150-1158 (2024)
Vishwakarma J, Sharma V, Kumar S, Ramachandran R
RgGuinier 3.0 nm
Dmax 8.4 nm
VolumePorod 81 nm3