2 hits found for Aspergillus fumigatus poly(ADP-ribosyl)polymerase 1 dBRCT

SASDXF9 – ...1 (Af-PARP1) with N-terminal dBRCT domain truncation Sample: Aspergillus fumigatus poly(ADP-ribosyl)polymerase 1 dBRCT monomer, 58 kDa Aspergillus fumigatus protein Buffer: ...150 mM NaCl, 2 mM TCEP, 2.5% (v/v) Glycerol, pH: 7.5 Experiment: SAXS data collected at ...1, Diamond Light Source on 2025 Jul 28 The BRCT domain enhances DNA binding and catalytic efficiency of fungal PARPs. Nat Commun 17(1) (2026) Bainbridge AG, Gianga TM, Hussain R, Parkin C, Longhurst AD, Helmstetter N, Farrer RA, Catania S, Siligardi G, Rack JGM RgGuinier 3.2 nm Dmax 10.9 nm VolumePorod 111 nm3

SASDXH9 – ...1 (Af-PARP1) with N-terminal dBRCT domain truncation:5'P nicked DNA complex Sample: Aspergillus fumigatus poly(ADP-ribosyl)polymerase 1 dBRCT monomer, 58 kDa Aspergillus fumigatus protein 5'Phosphorylated nicked DNA damage mimetic monomer, 14 kDa DNA Buffer: ...150 mM NaCl, 2 mM TCEP, 2.5% (v/v) Glycerol, pH: 7.5 Experiment: SAXS data collected at ...1, Diamond Light Source on ...14 The BRCT domain enhances DNA binding and catalytic efficiency of fungal PARPs. Nat Commun 17(1) (2026) Bainbridge AG, Gianga TM, Hussain R, Parkin C, Longhurst AD, Helmstetter N, Farrer RA, Catania S, Siligardi G, Rack JGM RgGuinier 3.5 nm Dmax 11.4 nm VolumePorod 151 nm3