2 hits found for Direct Repeat binding site with five-base-pair spacing

SASDXQ2 – RAR/RXR heterodimer : BMS493 : DR5 element Sample: Retinoic acid receptor alpha monomer, 39 kDa Mus musculus protein BMS493 (RAR inverse agonist ligand) monomer, 0 kDa Retinoid X receptor alpha monomer, 38 kDa Homo sapiens protein Direct Repeat binding site with five-base-pair spacing monomer, 13 kDa DNA Buffer: 20 mM Tris HCl, 75 mM NaCl, 75 mM KCl, 2 mM CHAPS, 4 mM MgCl₂, 12 mM TCEP, pH: 7.5 Experiment: SAXS data collected at SWING, SOLEIL on 2022 Sep 12 New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators. Nucleic Acids Res 53(18) (2025) Tambones I, Sagar A, Vankova P, Loginov D, Carivenc C, Rochel N, Bourguet W, Man P, Bernadó P, le Maire A RgGuinier 3.9 nm Dmax 14.3 nm VolumePorod 130 nm3

SASDXU2 – RAR/RXR heterodimer : BMS493 : NCoR NID : DR5 element Sample: Retinoic acid receptor alpha monomer, 39 kDa Mus musculus protein BMS493 (RAR inverse agonist ligand) monomer, 0 kDa Retinoid X receptor alpha monomer, 38 kDa Homo sapiens protein Direct Repeat binding site with five-base-pair spacing monomer, 13 kDa DNA Nuclear receptor corepressor 1 monomer, 29 kDa Mus musculus protein Buffer: 20 mM Tris HCl, 75 mM NaCl, 75 mM KCl, 2 mM CHAPS, 4 mM MgCl₂, 12 mM TCEP, pH: 7.5 Experiment: SAXS data collected at SWING, SOLEIL on 2022 Dec 12 New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators. Nucleic Acids Res 53(18) (2025) Tambones I, Sagar A, Vankova P, Loginov D, Carivenc C, Rochel N, Bourguet W, Man P, Bernadó P, le Maire A RgGuinier 5.7 nm Dmax 21.8 nm VolumePorod 363 nm3