2 hits found for Direct Repeat binding site with one-base-pair spacing

SASDXP2 – RAR/RXR heterodimer : BMS493 : DR1 element Sample: Retinoic acid receptor alpha monomer, 39 kDa Mus musculus protein BMS493 (RAR inverse agonist ligand) monomer, 0 kDa Retinoid X receptor alpha monomer, 38 kDa Homo sapiens protein Direct Repeat binding site with one-base-pair spacing monomer, 11 kDa DNA Buffer: 20 mM Tris HCl, 75 mM NaCl, 75 mM KCl, 2 mM CHAPS, 4 mM MgCl₂, 12 mM TCEP, pH: 7.5 Experiment: SAXS data collected at SWING, SOLEIL on 2022 Apr 20 New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators. Nucleic Acids Res 53(18) (2025) Tambones I, Sagar A, Vankova P, Loginov D, Carivenc C, Rochel N, Bourguet W, Man P, Bernadó P, le Maire A RgGuinier 3.8 nm Dmax 13.9 nm VolumePorod 120 nm3

SASDXT2 – RAR/RXR heterodimer : BMS493 : NCoR NID : DR1 element Sample: Retinoic acid receptor alpha monomer, 39 kDa Mus musculus protein BMS493 (RAR inverse agonist ligand) monomer, 0 kDa Retinoid X receptor alpha monomer, 38 kDa Homo sapiens protein Direct Repeat binding site with one-base-pair spacing monomer, 11 kDa DNA Nuclear receptor corepressor 1 monomer, 29 kDa Mus musculus protein Buffer: 20 mM Tris HCl, 75 mM NaCl, 75 mM KCl, 2 mM CHAPS, 4 mM MgCl₂, 12 mM TCEP, pH: 7.5 Experiment: SAXS data collected at SWING, SOLEIL on 2022 Apr 20 New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators. Nucleic Acids Res 53(18) (2025) Tambones I, Sagar A, Vankova P, Loginov D, Carivenc C, Rochel N, Bourguet W, Man P, Bernadó P, le Maire A RgGuinier 5.6 nm Dmax 21.8 nm VolumePorod 330 nm3