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4 hits found for Immunoglobulin heavy constant gamma 1

SASDSD2 – ...Heavy-chain-only nanobody C5-Fc (glycosylated)

Immunoglobulin heavy constant gamma 1 experimental SAS data
PYMOL model
Sample: Immunoglobulin heavy constant gamma 1 monomer, 78 kDa Homo sapiens protein
Buffer: ...138 mM NaCl, 2.6 mM KCl buffer, pH: 6
Experiment: SAXS data collected at ...1, Diamond Light Source on 2022 Sep 28
...heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions. J Biol Chem :105337 (2023)
Gao X, Thrush JW, Gor J, Naismith JH, Owens RJ, Perkins SJ
RgGuinier 3.9 nm
Dmax 13.2 nm
VolumePorod 157 nm3

SASDSE2 – ...Heavy-chain-only nanobody C5-Fc (Deglycosylated)

Immunoglobulin heavy constant gamma 1 experimental SAS data
PYMOL model
Sample: Immunoglobulin heavy constant gamma 1 monomer, 78 kDa Homo sapiens protein
Buffer: ...138 mM NaCl, 2.6 mM KCl buffer, pH: 6
Experiment: SAXS data collected at ...1, Diamond Light Source on 2022 Sep 28
...heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions. J Biol Chem :105337 (2023)
Gao X, Thrush JW, Gor J, Naismith JH, Owens RJ, Perkins SJ
RgGuinier 4.0 nm
Dmax 13.1 nm
VolumePorod 175 nm3

SASDDT4 – ...Immunoglobulin G1 (IgG1 Fc)

Immunoglobulin heavy constant gamma 1 experimental SAS data
BILBOMD model
Sample: Immunoglobulin heavy constant gamma 1 dimer, 53 kDa Homo sapiens protein
Buffer: 20mM HEPES, 50mM NaCl, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on ...16 Feb 17
...Immunoglobulin Fc Domain in Solution. Structure 26(7):1007-1014.e2 (2018)
Remesh SG, Armstrong AA, Mahan AD, Luo J, Hammel M
RgGuinier 2.6 nm
Dmax 10.0 nm
VolumePorod 70 nm3

SASDDV4 – ...Immunoglobulin G1, M135Y/S137T/T139E mutant (IgG1 Fc-YTE)

Immunoglobulin heavy constant gamma 1 M255Y/S257T/T259E experimental SAS data
BILBOMD model
Sample: Immunoglobulin heavy constant gamma 1 M255Y/S257T/T259E dimer, 53 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 50mM NaCl, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on ...16 Feb 17
...Immunoglobulin Fc Domain in Solution. Structure 26(7):1007-1014.e2 (2018)
Remesh SG, Armstrong AA, Mahan AD, Luo J, Hammel M
RgGuinier 2.7 nm
Dmax 10.0 nm
VolumePorod 74 nm3