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2 hits found for N-myc proto-oncogene protein, residues 1-69

SASDXU7 – N-Myc proto-oncogene protein residues 1-69

N-myc proto-oncogene protein, residues 1-69 experimental SAS data
N-myc proto-oncogene protein, residues 1-69 Kratky plot
Sample: N-myc proto-oncogene protein, residues 1-69 monomer, 8 kDa Homo sapiens protein
Buffer: 20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Nov 28
...N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A. Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
RgGuinier 2.4 nm
Dmax 11.0 nm
VolumePorod 12 nm3

SASDXX7 – N-Myc proto-oncogene residues 1-69 in complex with Aurora kinase A mutant C290A:C393A

N-myc proto-oncogene protein, residues 1-69Aurora kinase A mutant C290A:C393A experimental SAS data
N-myc proto-oncogene protein, residues 1-69 Aurora kinase A mutant C290A:C393A Kratky plot
Sample: N-myc proto-oncogene protein, residues 1-69 monomer, 8 kDa Homo sapiens protein
Aurora kinase A mutant C290A:C393A monomer, 33 kDa Homo sapiens protein
Buffer: 20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Nov 28
...N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A. Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
RgGuinier 2.5 nm
Dmax 10.2 nm
VolumePorod 62 nm3