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3 hits found for Tafamidis

SASDXW3 – Transthyretin tetramer

Transthyretin experimental SAS data
COOT model
Sample: Transthyretin tetramer, 55 kDa Homo sapiens protein
Buffer: 20 mM Tris, 50 mM NaCl, pH: 7
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2022 Sep 4
...tafamidis using SEC-SWAXS and NMR. J Appl Crystallogr 58(Pt 4):1373-1383 (2025)
Shih O, Feng YC, Agrawal S, Liao KF, Yeh YQ, Chang JW, Yu TY, Jeng US
RgGuinier 2.4 nm
Dmax 7.2 nm
VolumePorod 92 nm3

SASDXX3 – Transthyretin tetramer with over-saturated tolcapone

TransthyretinTolcapone experimental SAS data
COOT model
Sample: Transthyretin tetramer, 55 kDa Homo sapiens protein
Tolcapone dimer, 1 kDa
Buffer: 20 mM Tris, 50 mM NaCl, pH: 7
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 19
...tafamidis using SEC-SWAXS and NMR. J Appl Crystallogr 58(Pt 4):1373-1383 (2025)
Shih O, Feng YC, Agrawal S, Liao KF, Yeh YQ, Chang JW, Yu TY, Jeng US
RgGuinier 2.5 nm
Dmax 8.6 nm
VolumePorod 107 nm3

SASDXY3 – ...tafamidis

TransthyretinTafamidis experimental SAS data
COOT model
Sample: Transthyretin tetramer, 55 kDa Homo sapiens protein
Tafamidis dimer, 1 kDa
Buffer: 20 mM Tris, 50 mM NaCl, pH: 7
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 19
...tafamidis using SEC-SWAXS and NMR. J Appl Crystallogr 58(Pt 4):1373-1383 (2025)
Shih O, Feng YC, Agrawal S, Liao KF, Yeh YQ, Chang JW, Yu TY, Jeng US
RgGuinier 2.5 nm
Dmax 9.0 nm
VolumePorod 69 nm3