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4 hits found for octo-repeat PrP mRNA mutant

SASDDL5 – Mutant mammalian prion protein mRNA (octo-repeat PrP mRNA)

octo-repeat PrP mRNA mutant experimental SAS data
DAMFILT model
Sample: octo-repeat PrP mRNA mutant dimer, 144 kDa ...PrP ORF RNA
Buffer: 10 mM Tris buffer, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Jun 6
...mRNA forms stable A-helical hairpin structure rather than G-quadruplexes. Sci Rep 9(1):2465 (2019)
Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z
RgGuinier 7.0 nm
Dmax 24.0 nm
VolumePorod 150 nm3

SASDDM5 – Mutant mammalian prion protein mRNA (octo-repeat PrP mRNA) with KCl

octo-repeat PrP mRNA mutant experimental SAS data
DAMFILT model
Sample: octo-repeat PrP mRNA mutant dimer, 144 kDa ...PrP ORF RNA
Buffer: 10 mM Tris buffer with 100 mM KCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Jun 6
...mRNA forms stable A-helical hairpin structure rather than G-quadruplexes. Sci Rep 9(1):2465 (2019)
Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z
RgGuinier 9.0 nm
Dmax 33.0 nm
VolumePorod 210 nm3

SASDDN5 – Mutant mammalian prion protein mRNA (octo-repear PrP mRNA) with LiCl

octo-repeat PrP mRNA mutant experimental SAS data
DAMFILT model
Sample: octo-repeat PrP mRNA mutant dimer, 144 kDa ...PrP ORF RNA
Buffer: 10 mM Tris buffer with 100 mM LiCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Jun 6
...mRNA forms stable A-helical hairpin structure rather than G-quadruplexes. Sci Rep 9(1):2465 (2019)
Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z
RgGuinier 8.9 nm
Dmax 33.0 nm
VolumePorod 223 nm3

SASDDP5 – Mutant mammalian prion protein mRNA (octo-repear PrP mRNA) with KCl and pyridostatin (PDS)

octo-repeat PrP mRNA mutant experimental SAS data
DAMFILT model
Sample: octo-repeat PrP mRNA mutant dimer, 144 kDa ...PrP ORF RNA
Buffer: 10 mM Tris buffer with 100 mM KCl and 1 mM PDS, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Jun 6
...mRNA forms stable A-helical hairpin structure rather than G-quadruplexes. Sci Rep 9(1):2465 (2019)
Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z
RgGuinier 9.2 nm
Dmax 33.0 nm
VolumePorod 260 nm3