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1 hit found for Bruton's tyrosine kinase - Src homology 3-2 kinase domain

SASDF73Bruton's Tyrosine Kinase - SH3-SH2-kinase domain

Bruton's tyrosine kinase - Src homology 3-2 kinase domain experimental SAS data
Bruton's Tyrosine Kinase - SH3-SH2-kinase domain Rg histogram
Sample: Bruton's tyrosine kinase - Src homology 3-2 kinase domain monomer, 52 kDa Homo sapiens protein
Buffer: 20mM Tris, 150mM NaCl, 1mM TCEP, 5% glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Nov 2
...kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms Nature Communications 11(1) (2020)
Duarte D, Lamontanara A, La Sala G, Jeong S, Sohn Y, Panjkovich A, Georgeon S, Kükenshöner T, Marcaida M, Pojer F, De Vivo M, Svergun D, Kim H, Dal Peraro M, Hantschel O
RgGuinier 2.6 nm
Dmax 8.3 nm
VolumePorod 72 nm3