SASBDB entries for UniProt ID: P43490

SASDRZ7 – Human wild-type nicotinamide phosphoribosyltransferase (NAMPT)

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase
Nicotinamide phosphoribosyltransferase experimental SAS data
Nicotinamide phosphoribosyltransferase Kratky plot
Sample: Nicotinamide phosphoribosyltransferase dimer, 114 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.3 nm
Dmax 12.9 nm
VolumePorod 181 nm3

SASDR28 – Human wild-type nicotinamide phosphoribosyltransferase (NAMPT) in the presence of nicotinamide

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase
Nicotinamide phosphoribosyltransferase experimental SAS data
Nicotinamide phosphoribosyltransferase Kratky plot
Sample: Nicotinamide phosphoribosyltransferase dimer, 114 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM nicotinamide, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.2 nm
Dmax 12.8 nm
VolumePorod 166 nm3

SASDR38 – Human wild-type nicotinamide phosphoribosyltransferase (NAMPT) in the presence of nicotinic acid

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase
Nicotinamide phosphoribosyltransferase experimental SAS data
Nicotinamide phosphoribosyltransferase Kratky plot
Sample: Nicotinamide phosphoribosyltransferase dimer, 114 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM nicotinic acid, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.3 nm
Dmax 12.9 nm
VolumePorod 180 nm3

SASDR48 – Human wild-type nicotinamide phosphoribosyltransferase (NAMPT) in the presence of phosphoribosyl pyrophosphate

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase
Nicotinamide phosphoribosyltransferase experimental SAS data
Nicotinamide phosphoribosyltransferase Kratky plot
Sample: Nicotinamide phosphoribosyltransferase dimer, 114 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM phosphoribosyl pyrophosphate, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.3 nm
Dmax 12.9 nm
VolumePorod 173 nm3

SASDR58 – Human nicotinamide phosphoribosyltransferase Δ42-51 loop mutant (NAMPT Δ42-51)

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase Δ42-51
Nicotinamide phosphoribosyltransferase Δ42-51 experimental SAS data
Nicotinamide phosphoribosyltransferase Δ42-51 Kratky plot
Sample: Nicotinamide phosphoribosyltransferase Δ42-51 dimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.2 nm
Dmax 11.0 nm
VolumePorod 159 nm3

SASDR68 – Human nicotinamide phosphoribosyltransferase Δ42-51 loop mutant (NAMPT Δ42-51) in the presence of nicotinamide

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase Δ42-51
Nicotinamide phosphoribosyltransferase Δ42-51 experimental SAS data
Nicotinamide phosphoribosyltransferase Δ42-51 Kratky plot
Sample: Nicotinamide phosphoribosyltransferase Δ42-51 dimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM nicotinamide, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.2 nm
Dmax 10.9 nm
VolumePorod 151 nm3

SASDR78 – Human nicotinamide phosphoribosyltransferase Δ42-51 loop mutant (NAMPT Δ42-51) in the presence of nicotinic acid

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase Δ42-51
Nicotinamide phosphoribosyltransferase Δ42-51 experimental SAS data
Nicotinamide phosphoribosyltransferase Δ42-51 Kratky plot
Sample: Nicotinamide phosphoribosyltransferase Δ42-51 dimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM nicotinic acid, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.3 nm
Dmax 11.2 nm
VolumePorod 152 nm3

SASDR88 – Human nicotinamide phosphoribosyltransferase Δ42-51 loop mutant (NAMPT Δ42-51) in the presence of phosphoribosyl pyrophosphate

UniProt ID: P43490 (2-491) Nicotinamide phosphoribosyltransferase Δ42-51
Nicotinamide phosphoribosyltransferase Δ42-51 experimental SAS data
Nicotinamide phosphoribosyltransferase Δ42-51 Kratky plot
Sample: Nicotinamide phosphoribosyltransferase Δ42-51 dimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 6 mM MgCl2, 5% (v/v) glycerol, 1 mM phosphoribosyl pyrophosphate, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 20
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity. J Struct Biol :108004 (2023)
Houry D, Raasakka A, Ferrario E, Niere M, Bifulco E, Kursula P, Ziegler M
RgGuinier 3.2 nm
Dmax 11.4 nm
VolumePorod 154 nm3