Browse by DISSEMINATION: Published

SASDY97 – Alkaline phosphatase (ALP) under vis

Wild Alkaline Phosphatase under vis experimental SAS data
PYMOL model
Sample: Wild Alkaline Phosphatase under vis dimer, 97 kDa Escherichia coli protein
Buffer: 25 mM Tris, 100 mM NaCl, 2 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2024 Dec 23
Single-engineered-residue solvation perturbations regulate global protein architecture and function. Nat Commun (2026)
Liu Y, Zhai J, Cao S, Guo H, Zhang H, Song B, Guo J, Men D, He X, Li D
RgGuinier 2.8 nm
Dmax 9.0 nm
VolumePorod 75 nm3

SASDVB5 – CCDC6-RET fusion protein variant c

CCDC6-RET fusion protein variant c (K147M, Δ216-229) experimental SAS data
DAMMIN model
Sample: CCDC6-RET fusion protein variant c (K147M, Δ216-229) dimer, 86 kDa Homo sapiens protein
Buffer: 20 mM Tris, 500 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Sep 18
The oncogenic CCDC6-RET fusion protein is a dual ATP- and ADP-dependent kinase Nature Communications (2026)
Martín-Hurtado A, Contreras J, Sánchez-Wandelmer J, Zarzuela E, García F, Le Coq J, Boskovic J, Muñoz I, Gago F, Muñoz J, Isasa M, Plaza-Menacho I
RgGuinier 5.5 nm
Dmax 19.5 nm
VolumePorod 260 nm3

SASDX77 – Palladin Ig3-Ig4 tandem domain with linker swapped for the shorter Ig4-Ig5 Linnker

Palladin Ig3-45Linker_Ig4 experimental SAS data
Palladin Ig3-Ig4 tandem domain with linker swapped for the shorter Ig4-Ig5 Linnker Rg histogram
Sample: Palladin Ig3-45Linker_Ig4 monomer, 22 kDa Mus musculus protein
Buffer: HEPES, pH: 7.4
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2023 Aug 29
The role of linker length and composition in actin binding and bundling by palladin. Biochem J 483(3):301-318 (2026)
Sargent RA, Bradford CW, Hughes LM, Ta NH, Limpiado MJ, Vattepu R, Beck MR
RgGuinier 2.9 nm
Dmax 10.4 nm
VolumePorod 27 nm3

SASDXP7 – Human lung-associated vientovirus FB Replication-Associated Protein Apo form (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. PLoS Pathog 22(3):e1013997 (2026)
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
RgGuinier 5.2 nm
Dmax 155.0 nm

SASDXQ7 – Human lung-associated vientovirus FB Replication-Associated Protein Apo form (Rep) Hexamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Hexamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Hexamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Hexamer hexamer, 243670 kDa Vitentovirus RB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. PLoS Pathog 22(3):e1013997 (2026)
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
RgGuinier 4.7 nm
Dmax 144.0 nm
VolumePorod 488 nm3

SASDXR7 – Human lung-associated vientovirus FB Replication-Associated Protein ATP-bound (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. PLoS Pathog 22(3):e1013997 (2026)
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
RgGuinier 5.5 nm
Dmax 162.0 nm
VolumePorod 668 nm3

SASDXS7 – Human lung-associated vientovirus FB Replication-Associated Protein ADP-bound (Rep) Dodecamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Dodecamer dodecamer, 487340 kDa Vientovirus FB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. PLoS Pathog 22(3):e1013997 (2026)
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
RgGuinier 5.5 nm
Dmax 239.0 nm
VolumePorod 850 nm3

SASDXT7 – Human lung-associated vientovirus FB Replication-Associated Protein ADP-bound (Rep) Hexamer from SEC-SAXS with SVD-EFA analyses

Human lung-associated vientovirus FB Replication-Associated Protein Hexamer experimental SAS data
Human lung-associated vientovirus FB Replication-Associated Protein Hexamer Kratky plot
Sample: Human lung-associated vientovirus FB Replication-Associated Protein Hexamer hexamer, 243670 kDa Vitentovirus RB protein
Buffer: 20 mM HEPES, 300 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Jan 25
Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. PLoS Pathog 22(3):e1013997 (2026)
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD
RgGuinier 4.9 nm
Dmax 162.0 nm
VolumePorod 487 nm3

SASDYK4 – Heat shock cognate 71 kDa protein (Hsc70) T204A mutant with ATP (2 mg/ml)

Heat shock cognate 71 kDa protein experimental SAS data
Heat shock cognate 71 kDa protein Kratky plot
Sample: Heat shock cognate 71 kDa protein, 71 kDa protein
Buffer: 20 mM HEPES, 150 mM KCl, 10 mM MgCl2, 1 mM TCEP, 1 mM ATP, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2025 Mar 6
Advances on the large-scale bacterial production and stable phosphorylation of Hsc70 Protein Expression and Purification :106923 (2026)
Kley N, Hecht-Bucher M, Itzen A
RgGuinier 4.1 nm
Dmax 17.5 nm
VolumePorod 143 nm3

SASDYL4 – Heat shock cognate 71 kDa protein (Hsc70) T204A mutant with ATP (3 mg/ml)

Heat shock cognate 71 kDa protein experimental SAS data
Heat shock cognate 71 kDa protein Kratky plot
Sample: Heat shock cognate 71 kDa protein, 71 kDa protein
Buffer: 20 mM HEPES, 150 mM KCl, 10 mM MgCl2, 1 mM TCEP, 1 mM ATP, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2025 Mar 6
Advances on the large-scale bacterial production and stable phosphorylation of Hsc70 Protein Expression and Purification :106923 (2026)
Kley N, Hecht-Bucher M, Itzen A
RgGuinier 4.1 nm
Dmax 18.3 nm
VolumePorod 143 nm3