Browse by DISSEMINATION: Published

SASDXJ3 – Human major vault protein

Major vault protein experimental SAS data
OTHER [STATIC IMAGE] model
Sample: Major vault protein, 7747 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2022 Jun 8
Structural flexibility of the human vault particle revealed by high-resolution cryo-EM and molecular dynamics simulations. Nat Commun (2026)
Lapenta F, Palacio-Rodriguez K, Cruz-León S, Marrancone S, Aupič J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G
RgGuinier 16.3 nm
Dmax 65.0 nm
VolumePorod 16650 nm3

SASDZW5 – The FAA Condensation Domain, OaaC from Coprococcus Eutactus (Plipastatin synthase subunit A)

Condensation Domain from Coprococcus Eutactus experimental SAS data
GROMACS model
Sample: Condensation Domain from Coprococcus Eutactus dimer, 108 kDa Coprococcus eutactus ATCC … protein
Buffer: 10mM HEPES pH 7.5, 50mM NaCl, 0.2mM TCEP, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2022 Dec 16
Structure of a Stand-Alone Homodimeric NRPS Condensation Domain Reveals Occlusion of the Canonical Carrier-Protein Interface (2026)
Singh J, Grant T, Gulick A
RgGuinier 3.2 nm
Dmax 9.5 nm
VolumePorod 184 nm3

SASDY63 – human telomeric g-quadruplex (Tel50)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.1 nm

SASDY73 – human telomeric g-quadruplex (Tel26)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 1.3 nm

SASDY83 – human telomeric g-quadruplex Tel50+BRACO-19 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm

SASDY93 – human telomeric g-quadruplex Tel50+BRACO-19 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm

SASDYA3 – human telomeric g-quadruplex Tel50+BRACO-19 (1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm

SASDYB3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm

SASDYC3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm

SASDYD3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: Human telomeric g-quadruplex, 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers. Nucleic Acids Res 54(8) (2026)
Bertini L, Libera V, Arciuolo V, Trapella M, Marzano S, Mostarac D, Schirò G, Petrillo C, Giancola C, De Michele C, Amato J, Comez L, Pagano B, Paciaroni A
RgGuinier 2.0 nm