Browse by MODEL: Ensemble

SASDVY3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM EDTA, 0.5 mM deuterated n-Dodecyl-β-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.2 nm
Dmax 18.4 nm
VolumePorod 558 nm3

SASDVX3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM CaCl2, 0.5 mM deuterated n-Dodecyl-B-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.1 nm
Dmax 17.1 nm
VolumePorod 581 nm3

SASDVQ7 – PABL2 (Partner and localizer of BRCA2) L24A mutant

Partner and localizer of BRCA2 (L24A) experimental SAS data
PABL2 (Partner and localizer of BRCA2) L24A mutant Rg histogram
Sample: Partner and localizer of BRCA2 (L24A) monomer, 23 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 160 mM NaCl, 0.5 mM TCEP pH 7.5, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Dec 9
The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction. iScience 27(12):111259 (2024)
Kyriukha Y, Watkins MB, Redington JM, Chintalapati N, Ganti A, Dastvan R, Uversky VN, Hopkins JB, Pozzi N, Korolev S
RgGuinier 5.2 nm
Dmax 21.6 nm
VolumePorod 127 nm3

SASDRV9 – Regulator of telomere elongation helicase 1, C - terminal

Regulator of telomere elongation helicase 1 (Isoform 6, 756-1300) experimental SAS data
Regulator of telomere elongation helicase 1, C - terminal Rg histogram
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 756-1300) monomer, 59 kDa Homo sapiens protein
Buffer: 50 mM Hepes, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 4.9 nm
Dmax 15.3 nm
VolumePorod 132 nm3

SASDRX9 – Regulator of telomere elongation helicase 1, C - terminal, CT-S fragment

Regulator of telomere elongation helicase 1 (Isoform 6, 756-1219) experimental SAS data
Regulator of telomere elongation helicase 1, C - terminal, CT-S fragment Rg histogram
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 756-1219) monomer, 50 kDa Homo sapiens protein
Buffer: 50 mM Hepes, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 4.9 nm
Dmax 18.0 nm
VolumePorod 121 nm3

SASDRW9 – Regulator of telomere elongation helicase 1, HHD1-HHD2 fragment

Regulator of telomere elongation helicase 1 (Isoform 6, 889-1147) experimental SAS data
Regulator of telomere elongation helicase 1, HHD1-HHD2 fragment Rg histogram
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 889-1147) monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Hepes, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 3.4 nm
Dmax 10.1 nm
VolumePorod 36 nm3

SASDTU5 – SemDΔAPH bound to BR-GBD (actin nucleation-promoting factor WASL)

Uncharacterized proteinActin nucleation-promoting factor WASL experimental SAS data
SemDΔAPH bound to BR-GBD (actin nucleation-promoting factor WASL) Rg histogram
Sample: Uncharacterized protein monomer, 35 kDa Chlamydia pneumoniae protein
Actin nucleation-promoting factor WASL monomer, 19 kDa Rattus norvegicus protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, 3 %Glycerol, pH: 8.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Dec 14
The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry Nature Communications 15(1) (2024)
Kocher F, Applegate V, Reiners J, Port A, Spona D, Hänsch S, Mirzaiebadizi A, Ahmadian M, Smits S, Hegemann J, Mölleken K
RgGuinier 4.2 nm
Dmax 15.9 nm
VolumePorod 102 nm3

SASDUR3 – C-terminal domain of the W protein (CTDw) of Nipah Virus (NiV)

Protein W experimental SAS data
C-terminal domain of the W protein (CTDw) of Nipah Virus (NiV) Rg histogram
Sample: Protein W monomer, 6 kDa Henipavirus nipahense protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Apr 16
Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N- and C-terminal constituent domains. FEBS J (2024)
Pesce G, Gondelaud F, Ptchelkine D, Bignon C, Fourquet P, Longhi S
RgGuinier 2.1 nm
Dmax 7.8 nm
VolumePorod 8 nm3

SASDUQ3 – C-terminal domain of the W protein (CTDw) of Hendra Virus (HeV)

Protein W experimental SAS data
C-terminal domain of the W protein (CTDw) of Hendra Virus (HeV) Rg histogram
Sample: Protein W monomer, 6 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Apr 16
Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N- and C-terminal constituent domains. FEBS J (2024)
Pesce G, Gondelaud F, Ptchelkine D, Bignon C, Fourquet P, Longhi S
RgGuinier 2.1 nm
Dmax 7.4 nm
VolumePorod 8 nm3

SASDQ49 – His-Tagged full length DNA repair protein RAD52 homolog

DNA repair protein RAD52 homolog experimental SAS data
His-Tagged full length DNA repair protein RAD52 homolog Rg histogram
Sample: DNA repair protein RAD52 homolog undecamer, 528 kDa Homo sapiens protein
Buffer: 20 mM Tris pH 7.5, 250 mM NaCl, 1% glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2022 Jul 21
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution Communications Biology 7(1) (2024)
Balboni B, Marotta R, Rinaldi F, Milordini G, Varignani G, Girotto S, Cavalli A
RgGuinier 8.0 nm
Dmax 40.2 nm
VolumePorod 1218 nm3