Browse by MODEL: No model

SASDG78 – Apolipoprotein E2 bound to 37 µM Suramin

Apolipoprotein E2Suramin experimental SAS data
Apolipoprotein E2 Suramin Kratky plot
Sample: Apolipoprotein E2 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 5.9 nm
Dmax 19.8 nm

SASDG88 – Apolipoprotein E2 bound to 12 µM Suramin

Apolipoprotein E2Suramin experimental SAS data
Apolipoprotein E2 Suramin Kratky plot
Sample: Apolipoprotein E2 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 6.1 nm
Dmax 20.3 nm

SASDG98 – Apolipoprotein E2 bound to 4 µM Suramin

Apolipoprotein E2Suramin experimental SAS data
Apolipoprotein E2 Suramin Kratky plot
Sample: Apolipoprotein E2 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 6.1 nm
Dmax 20.5 nm

SASDGA8 – Apolipoprotein E3 bound to 330 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 5.2 nm
Dmax 18.6 nm

SASDGB8 – Apolipoprotein E3 bound to 110 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 5.6 nm
Dmax 19.1 nm

SASDGC8 – Apolipoprotein E3 bound to 37 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 6.0 nm
Dmax 20.3 nm

SASDGD8 – Apolipoprotein E3 bound to 12 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 6.1 nm
Dmax 20.0 nm

SASDGE8 – Apolipoprotein E3 bound to 4 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 6.2 nm
Dmax 20.1 nm

SASDGF8 – Apolipoprotein E4 bound to 330 µM Suramin

Apolipoprotein E4Suramin experimental SAS data
Apolipoprotein E4 Suramin Kratky plot
Sample: Apolipoprotein E4 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 5.4 nm
Dmax 19.6 nm

SASDGG8 – Apolipoprotein E4 bound to 110 µM Suramin

Apolipoprotein E4Suramin experimental SAS data
Apolipoprotein E4 Suramin Kratky plot
Sample: Apolipoprotein E4 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Therapeutic approaches to ApoE University of Sussex PhD thesis 2019 (2019)
Lucas Kraft
RgGuinier 5.5 nm
Dmax 19.5 nm