Browse by MODEL: No model

SASDT77 – Truncated Neurofilament low intrinsically disordered tail domain (amino acids 441-543) polyelectrolyte - 0.78 mg/ml - 20 mM Tris pH 8.0, 500 mM NaCl

Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) experimental SAS data
Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) Kratky plot
Sample: Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) monomer, 12 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.00, 500 mM NaCl, pH:
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Sep 7
From isolated polyelectrolytes to star-like assemblies: the role of sequence heterogeneity on the statistical structure of the intrinsically disordered neurofilament-low tail domain. Eur Phys J E Soft Matter 47(2):13 (2024)
Kravikass M, Koren G, Saleh OA, Beck R
RgGuinier 4.0 nm

SASDT87 – Truncated Neurofilament low intrinsically disordered tail domain (amino acids 441-543) polyelectrolyte - 0.38 mg/ml - 20 mM Tris pH 8.0, 500 mM NaCl

Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) experimental SAS data
Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) Kratky plot
Sample: Neurofilament light polypeptide (T445N; C-terminus, amino acids 441-543) monomer, 12 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.00, 500 mM NaCl, pH:
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Sep 7
From isolated polyelectrolytes to star-like assemblies: the role of sequence heterogeneity on the statistical structure of the intrinsically disordered neurofilament-low tail domain. Eur Phys J E Soft Matter 47(2):13 (2024)
Kravikass M, Koren G, Saleh OA, Beck R
RgGuinier 4.2 nm

SASDKH8 – C-Terminal Cytoplasmatic Region of the Translocated Intimin Receptor

Translocated intimin receptor Tir experimental SAS data
Translocated intimin receptor Tir Kratky plot
Sample: Translocated intimin receptor Tir monomer, 18 kDa Escherichia coli O127:H6 … protein
Buffer: 20 mM Sodium Phosphate, 150 mM NaCl, 1 mM EDTA, pH: 6.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Sep 15
The pathogen-encoded signalling receptor Tir exploits host-like intrinsic disorder for infection. Commun Biol 7(1):179 (2024)
Vieira MFM, Hernandez G, Zhong Q, Arbesú M, Veloso T, Gomes T, Martins ML, Monteiro H, Frazão C, Frankel G, Zanzoni A, Cordeiro TN
RgGuinier 3.8 nm
Dmax 12.8 nm
VolumePorod 46 nm3

SASDRQ5 – Small beta-barrel domain in the N-terminal region of the Translocated Intimin Receptor (Tir76-180)

Translocated intimin receptor Tir experimental SAS data
Translocated intimin receptor Tir Kratky plot
Sample: Translocated intimin receptor Tir monomer, 12 kDa Escherichia coli O127:H6 … protein
Buffer: 100 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Nov 21
The pathogen-encoded signalling receptor Tir exploits host-like intrinsic disorder for infection. Commun Biol 7(1):179 (2024)
Vieira MFM, Hernandez G, Zhong Q, Arbesú M, Veloso T, Gomes T, Martins ML, Monteiro H, Frazão C, Frankel G, Zanzoni A, Cordeiro TN
RgGuinier 1.7 nm
Dmax 7.0 nm
VolumePorod 21 nm3

SASDTM5 – Proteusin peptide

NHLP leader peptide family natural product (I56V) experimental SAS data
NHLP leader peptide family natural product (I56V) Kratky plot
Sample: NHLP leader peptide family natural product (I56V) monomer, 9 kDa Methylovulum psychrotolerans protein
Buffer: 20 mM sodium phosphate (pH 7.5), 100 mM NaCl and 48 µM FAD, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jul 28
Disordered regions in proteusin peptides guide post-translational modification by a flavin-dependent RiPP brominase. Nat Commun 15(1):1265 (2024)
Nguyen NA, Vidya FNU, Yennawar NH, Wu H, McShan AC, Agarwal V
RgGuinier 1.9 nm
Dmax 5.5 nm
VolumePorod 39 nm3

SASDRJ9 – High mobility group protein B1/Stromal cell-derived factor 1 complex (HMGB1-CXCL12)

Stromal cell-derived factor 1High mobility group protein B1 (D189E, E202D, E215D) experimental SAS data
Stromal cell-derived factor 1 High mobility group protein B1 (D189E, E202D, E215D) Kratky plot
Sample: Stromal cell-derived factor 1 monomer, 9 kDa Homo sapiens protein
High mobility group protein B1 (D189E, E202D, E215D) monomer, 25 kDa Rattus norvegicus protein
Buffer: 20 mM Tris, 50 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2021 Nov 11
The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12. Nat Commun 15(1):1201 (2024)
Mantonico MV, De Leo F, Quilici G, Colley LS, De Marchis F, Crippa M, Mezzapelle R, Schulte T, Zucchelli C, Pastorello C, Carmeno C, Caprioglio F, Ricagno S, Giachin G, Ghitti M, Bianchi ME, Musco G
RgGuinier 2.9 nm
Dmax 10.5 nm
VolumePorod 72 nm3

SASDT29 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 705 nm3

SASDT39 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 35 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.4 nm
VolumePorod 704 nm3

SASDT49 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 44 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.6 nm
VolumePorod 702 nm3

SASDT59 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 50 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 29
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.6 nm
VolumePorod 699 nm3