Browse by MODEL: No model

SASDSA6 – Human Ubiquilin-2 (UBQLN2)

Ubiquilin-2 experimental SAS data
Ubiquilin-2 Kratky plot
Sample: Ubiquilin-2 dimer, 131 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 8
Short disordered N-termini & proline-rich domain are major regulators of UBQLN1/2/4 phase separation. Biophys J (2023)
Dao TP, Rajendran A, Galagedera SKK, Haws W, Castañeda CA
RgGuinier 5.2 nm
Dmax 22.5 nm
VolumePorod 330 nm3

SASDSB6 – Human Ubiquilin-4 (UBQLN4)

Ubiquilin-4 experimental SAS data
Ubiquilin-4 Kratky plot
Sample: Ubiquilin-4 dimer, 128 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 26
Short disordered N-termini & proline-rich domain are major regulators of UBQLN1/2/4 phase separation. Biophys J (2023)
Dao TP, Rajendran A, Galagedera SKK, Haws W, Castañeda CA
RgGuinier 5.1 nm
Dmax 21.7 nm
VolumePorod 333 nm3

SASDTN5 – The D2 domain of E3 ubiquitin-protein ligase DTX3L (I101-Q200)

E3 ubiquitin-protein ligase DTX3L experimental SAS data
E3 ubiquitin-protein ligase DTX3L Kratky plot
Sample: E3 ubiquitin-protein ligase DTX3L tetramer, 46 kDa Homo sapiens protein
Buffer: 30 mM HEPES, 350 mM NaCl, 5% (v/v) glycerol, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Dec 6
Oligomerisation mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor. bioRxiv (2023)
Vela-Rodríguez C, Yang C, Alanen HI, Eki R, Abbas TA, Maksimainen MM, Glumoff T, Duman R, Wagner A, Paschal BM, Lehtiö L
RgGuinier 2.9 nm
Dmax 112.0 nm
VolumePorod 91 nm3

SASDNP8 – High mannose contactin-2 immunoglobulin domains1-6, 1μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 5.1 nm
Dmax 20.0 nm
VolumePorod 140 nm3

SASDNQ8 – High mannose contactin 2 immunoglobulin domains1-6, 3μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 5.3 nm
Dmax 20.0 nm
VolumePorod 300 nm3

SASDNR8 – High mannose contactin-2 immunoglobulin domains1-6, 6μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 5.4 nm
Dmax 21.0 nm
VolumePorod 325 nm3

SASDNS8 – High mannose contactin-2 immunoglobulin domains1-6, 13μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 5.5 nm
Dmax 21.4 nm
VolumePorod 350 nm3

SASDNT8 – High mannose contactin-2 immunoglobulin domains1-6, 26μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 6.0 nm
Dmax 30.0 nm
VolumePorod 380 nm3

SASDNU8 – High mannose contactin-2 immunoglobulin domains1-6, 52μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 6.1 nm
Dmax 32.0 nm
VolumePorod 408 nm3

SASDNV8 – Complex glycan contactin-2 immunoglobulin domains1-6, 1μM

Contactin-2 experimental SAS data
Contactin-2 Kratky plot
Sample: Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 17
Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B
RgGuinier 5.6 nm
Dmax 25.0 nm
VolumePorod 230 nm3