Browse by MACROMOLECULE type: nucleic acid

SASDW62 – 3 mg/ml β-chitin nanofibers from squid pens in 47 % D₂O - USANS

β-chitin nanofibers from squid pens experimental SAS data
β-chitin nanofibers from squid pens Kratky plot
Sample: Β-chitin nanofibers from squid pens None, Squid
Buffer: 20 mM acetate, 47% v/v D₂O, pH: 5
Experiment: SANS data collected at BT5 USANS, NIST Center for Neutron Research on 2020 Dec 4
Tangled up in fibers: How a lytic polysaccharide monooxygenase binds its chitin substrate

SASDUS8 – HIV-1 DIS RNA with a CCCCCC apical loop (DIS-C)

HIV-1 dimerization initiation site with a CCCCCC apical loop experimental SAS data
RNAMASONRY model
Sample: HIV-1 dimerization initiation site with a CCCCCC apical loop monomer, 9 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 20
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 1.5 nm
Dmax 4.6 nm
VolumePorod 11 nm3

SASDUT8 – HIV-1 DIS RNA with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension (DIS-Gk)

HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension experimental SAS data
RNAMASONRY model
Sample: HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension monomer, 21 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 20
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 2.6 nm
Dmax 10.5 nm
VolumePorod 28 nm3

SASDUU8 – HIV-1 DIS-C:DIS-Gk RNA heterocomplex

HIV-1 dimerization initiation site with a CCCCCC apical loopHIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension experimental SAS data
RNAMASONRY model
Sample: HIV-1 dimerization initiation site with a CCCCCC apical loop monomer, 9 kDa RNA
HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension monomer, 21 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 20
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 3.5 nm
Dmax 13.5 nm
VolumePorod 40 nm3

SASDUV8 – HIV-1 ²H-DIS-C:¹H-DIS-Gk RNA heterocomplex (DIS-Gk contrast matched in 65% v/v D₂O - SANS data)

HIV-1 dimerization initiation site with a CCCCCC apical loopHIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension experimental SAS data
RNAMASONRY model
Sample: HIV-1 dimerization initiation site with a CCCCCC apical loop monomer, 9 kDa RNA
HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension monomer, 21 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SANS data collected at CG-3, High Flux Isotope Reactor on 2022 Oct 5
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 1.6 nm
Dmax 5.3 nm

SASDUW8 – HIV-1 ¹H-DIS-C:²H(42%)-DIS-Gk RNA heterocomplex (DIS-Gk contrast matched in 90% v/v D₂O - SANS data)

HIV-1 dimerization initiation site with a CCCCCC apical loopHIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension experimental SAS data
RNAMASONRY model
Sample: HIV-1 dimerization initiation site with a CCCCCC apical loop monomer, 9 kDa RNA
HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension monomer, 21 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SANS data collected at CG-3, High Flux Isotope Reactor on 2023 Sep 15
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 1.4 nm
Dmax 4.6 nm

SASDUX8 – HIV-1 ²H(42%)-DIS-C:¹H-DIS-Gk RNA heterocomplex (DIS-C contrast matched in 90% v/v D₂O - SANS data)

HIV-1 dimerization initiation site with a CCCCCC apical loopHIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension experimental SAS data
RNAMASONRY model
Sample: HIV-1 dimerization initiation site with a CCCCCC apical loop monomer, 9 kDa RNA
HIV-1 DIS with a GGGGGG apical loop, UCU bulge, and 16 bp helical extension monomer, 21 kDa RNA
Buffer: 50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment: SANS data collected at CG-3, High Flux Isotope Reactor on 2023 Sep 15
Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering. Structure (2025)
Munsayac A, Leite WC, Hopkins JB, Hall I, O'Neill HM, Keane SC
RgGuinier 2.9 nm
Dmax 9.7 nm

SASDVZ3 – SARS-CoV2 RNA pseudoknot at 4 mg/mL

SARS-CoV2 RNA pseudoknot experimental SAS data
SARS-CoV2 RNA pseudoknot Kratky plot
Sample: SARS-CoV2 RNA pseudoknot monomer, 22 kDa Severe acute respiratory … RNA
Buffer: 25 mM potassium phosphate, 50 mM KCl, pH: 6.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Optimization of Structure‐Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS‐CoV‐2 Angewandte Chemie International Edition (2025)
Ceylan B, Adam J, Toews S, Kaiser F, Dörr J, Scheppa D, Tants J, Smart A, Schoth J, Philipp S, Stirnal E, Ferner J, Richter C, Sreeramulu S, Caliskan N, Schlundt A, Weigand J, Göbel M, Wacker A, Schwalbe H
RgGuinier 2.3 nm
Dmax 7.9 nm
VolumePorod 29 nm3

SASDV24 – SARS-CoV2 RNA pseudoknot at 2 mg/mL

SARS-CoV2 RNA pseudoknot experimental SAS data
SARS-CoV2 RNA pseudoknot Kratky plot
Sample: SARS-CoV2 RNA pseudoknot monomer, 22 kDa Severe acute respiratory … RNA
Buffer: 25 mM potassium phosphate, 50 mM KCl, pH: 6.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Optimization of Structure‐Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS‐CoV‐2 Angewandte Chemie International Edition (2025)
Ceylan B, Adam J, Toews S, Kaiser F, Dörr J, Scheppa D, Tants J, Smart A, Schoth J, Philipp S, Stirnal E, Ferner J, Richter C, Sreeramulu S, Caliskan N, Schlundt A, Weigand J, Göbel M, Wacker A, Schwalbe H
RgGuinier 2.5 nm
Dmax 8.9 nm
VolumePorod 32 nm3

SASDV34 – SARS-CoV2 RNA pseudoknot at 1 mg/mL

SARS-CoV2 RNA pseudoknot experimental SAS data
SARS-CoV2 RNA pseudoknot Kratky plot
Sample: SARS-CoV2 RNA pseudoknot monomer, 22 kDa Severe acute respiratory … RNA
Buffer: 25 mM potassium phosphate, 50 mM KCl, pH: 6.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Optimization of Structure‐Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS‐CoV‐2 Angewandte Chemie International Edition (2025)
Ceylan B, Adam J, Toews S, Kaiser F, Dörr J, Scheppa D, Tants J, Smart A, Schoth J, Philipp S, Stirnal E, Ferner J, Richter C, Sreeramulu S, Caliskan N, Schlundt A, Weigand J, Göbel M, Wacker A, Schwalbe H
RgGuinier 2.5 nm
Dmax 9.5 nm
VolumePorod 32 nm3