Browse by MACROMOLECULE type: nucleic acid

SASDW43 – Telomere DNA G-quadruplex (2GKU) at neutral pH

Telomere DNA G-quadruplex Hybrid-1 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-1 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-1 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 11
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 1.2 nm
Dmax 3.8 nm
VolumePorod 8 nm3

SASDW53 – Telomere DNA G-quadruplex (2JSL) at neutral pH

Telomere DNA G-quadruplex Hybrid-2 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-2 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 11
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 1.2 nm
Dmax 3.8 nm
VolumePorod 8 nm3

SASDW63 – Telomere DNA G-quadruplex (2GKU) at neutral pH with LiCl

Telomere DNA G-quadruplex Hybrid-1 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-1 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-1 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Li2HPO4, 2 mM LiH2PO4, 1 mM EDTA, 185 mM LiCl, pH 7.2, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 11
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 1.2 nm
Dmax 4.3 nm
VolumePorod 7 nm3

SASDW73 – Telomere DNA G-quadruplex (2JSL) at neutral pH with LiCl

Telomere DNA G-quadruplex Hybrid-2 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-2 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Li2HPO4, 2 mM LiH2PO4, 1 mM EDTA, 185 mM LiCl, pH 7.2, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 12
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 1.3 nm
Dmax 5.1 nm
VolumePorod 8 nm3

SASDW83 – Telomere DNA G-quadruplex (2GKU) at alkaline pH

Telomere DNA G-quadruplex Hybrid-1 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-1 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-1 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH 11.5, pH: 11.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 12
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 2.4 nm
Dmax 8.3 nm
VolumePorod 12 nm3

SASDW93 – Telomere DNA G-quadruplex (2JSL) at alkaline pH

Telomere DNA G-quadruplex Hybrid-2 form experimental SAS data
Telomere DNA G-quadruplex Hybrid-2 form Kratky plot
Sample: Telomere DNA G-quadruplex Hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH 11.5, pH: 11.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 12
Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering. Nucleic Acids Res 53(3) (2025)
Monsen RC, Sabo TM, Gray R, Hopkins JB, Chaires JB
RgGuinier 2.4 nm
Dmax 8.7 nm
VolumePorod 12 nm3

SASDTA7 – RNase P RNA in the presence of 0.1 mM MgCl2

RNase P RNA experimental SAS data
RNase P RNA Kratky plot
Sample: RNase P RNA monomer, 135 kDa Geobacillus stearothermophilus RNA
Buffer: 100 mM NaCl, 0.1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at Rigaku BIOSAXS-2000 [duplicate], Center for Cancer Research,National Cancer Institute on 2023 Nov 3
The conformational space of RNase P RNA in solution Nature (2024)
Lee Y, Degenhardt M, Skeparnias I, Degenhardt H, Bhandari Y, Yu P, Stagno J, Fan L, Zhang J, Wang Y
RgGuinier 6.1 nm
Dmax 21.8 nm
VolumePorod 813 nm3

SASDTB7 – RNase P RNA in the presence of 1.0 mM MgCl2

RNase P RNA experimental SAS data
RNase P RNA Kratky plot
Sample: RNase P RNA monomer, 135 kDa Geobacillus stearothermophilus RNA
Buffer: 100 mM NaCl, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at Rigaku BIOSAXS-2000 [duplicate], Center for Cancer Research,National Cancer Institute on 2023 Nov 3
The conformational space of RNase P RNA in solution Nature (2024)
Lee Y, Degenhardt M, Skeparnias I, Degenhardt H, Bhandari Y, Yu P, Stagno J, Fan L, Zhang J, Wang Y
RgGuinier 5.2 nm
Dmax 15.6 nm
VolumePorod 370 nm3

SASDTC7 – RNase P RNA in the presence of 1.5 mM MgCl2

RNase P RNA experimental SAS data
RNase P RNA Kratky plot
Sample: RNase P RNA monomer, 135 kDa Geobacillus stearothermophilus RNA
Buffer: 100 mM NaCl,1.5 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at Rigaku BIOSAXS-2000 [duplicate], Center for Cancer Research,National Cancer Institute on 2023 Nov 3
The conformational space of RNase P RNA in solution Nature (2024)
Lee Y, Degenhardt M, Skeparnias I, Degenhardt H, Bhandari Y, Yu P, Stagno J, Fan L, Zhang J, Wang Y
RgGuinier 5.0 nm
Dmax 16.2 nm
VolumePorod 352 nm3

SASDTD7 – RNase P RNA in the presence of 2.0 mM MgCl2

RNase P RNA experimental SAS data
RNase P RNA Kratky plot
Sample: RNase P RNA monomer, 135 kDa Geobacillus stearothermophilus RNA
Buffer: 100 mM NaCl, 2.0 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at Rigaku BIOSAXS-2000 [duplicate], Center for Cancer Research,National Cancer Institute on 2023 Nov 3
The conformational space of RNase P RNA in solution Nature (2024)
Lee Y, Degenhardt M, Skeparnias I, Degenhardt H, Bhandari Y, Yu P, Stagno J, Fan L, Zhang J, Wang Y
RgGuinier 5.0 nm
Dmax 15.7 nm
VolumePorod 316 nm3