Small Angle Scattering Biological Data Bank SASBDB

Browse by MACROMOLECULE type: other and no molecule

SASDQ99 – Immunoglobulin G1 (pH 2, 0 M NaCl), SEC-SAXS data

humanized immunoglobulin G1 monoclonal antibody experimental SAS data

humanized immunoglobulin G1 monoclonal antibody Kratky plot

Sample:	Humanized immunoglobulin G1 monoclonal antibody monomer, 148 kDa Mouse/human (chimera)
Buffer:	100 mM glycine-HCl, pH: 2
Experiment:	SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2016 Mar 2

Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies The Journal of Physical Chemistry Letters :3898-3906 (2023)
Imamura H, Ooishi A, Honda S

R_g^Guinier	5.1	nm
D_max	17.6	nm
Volume^Porod	260	nm³

SASDQA9 – Immunoglobulin G1 (pH 2, 0.2 M NaCl), SEC-SAXS data

Sample:	Humanized immunoglobulin G1 monoclonal antibody monomer, 148 kDa Mouse/human (chimera)
Buffer:	100 mM glycine-HCl, 200 mM NaCl, pH: 2
Experiment:	SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2017 Mar 5

Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies The Journal of Physical Chemistry Letters :3898-3906 (2023)
Imamura H, Ooishi A, Honda S

R_g^Guinier	4.1	nm
D_max	14.2	nm
Volume^Porod	240	nm³

SASDR82 – Alpha cyclodextrin - 50 mg/ml aqueous solution measured to 235 inverse nm

alpha cyclodextrin experimental SAS data

Sample:	Alpha cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

Extended q‐range X‐ray Scattering Reveals High‐Resolution Structural Details of Biomacromolecules in Aqueous Solutions Chemistry – A European Journal (2023)
Chen J, Borkiewicz O, Grishaev A, Zhang F, Bera M, Ruett U, Levin I

R_g^Guinier

0.6

SASDR92 – Alpha cyclodextrin - 25 mg/ml aqueous solution measured to 235 inverse nm

Sample:	Alpha cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.6

SASDRA2 – Alpha cyclodextrin - 12.5 mg/ml aqueous solution measured to 235 inverse nm

Sample:	Alpha cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.6

SASDRB2 – Beta cyclodextrin - 18 mg/ml aqueous solution measured to 238 inverse nm

Sample:	Beta Cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.7

SASDRC2 – Beta cyclodextrin - 12.5 mg/ml aqueous solution measured to 238 inverse nm

Sample:	Beta Cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.7

SASDRD2 – Gamma cyclodextrin - 50 mg/ml aqueous solution measured to 238 inverse nm

Gamma Cyclodextrin experimental SAS data

Sample:	Gamma Cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.7

SASDRE2 – Gamma cyclodextrin - 25 mg/ml aqueous solution measured to 238 inverse nm

Sample:	Gamma Cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.7

SASDRF2 – Gamma cyclodextrin - 12.5 mg/ml aqueous solution measured to 238 inverse nm

Sample:	Gamma Cyclodextrin monomer, 1 kDa
Buffer:	water, pH: 7
Experiment:	SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2

R_g^Guinier

0.7

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