Browse by ORGANISM: Homo sapiens (Human)

SASDVM4 – Immunoglobulin light chain H7

Immunoglobulin light chain H7 experimental SAS data
MODELLER model
Sample: Immunoglobulin light chain H7 dimer, 45 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 May 12
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.5 nm
Dmax 8.4 nm
VolumePorod 54 nm3

SASDVN4 – Immunoglobulin light chain H18

Immunoglobulin light chain H18 experimental SAS data
SWISSMODEL model
Sample: Immunoglobulin light chain H18 dimer, 43 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2021 Jul 2
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.6 nm
Dmax 8.2 nm
VolumePorod 58 nm3

SASDVP4 – Immunoglobulin light chain M7

Immunoglobulin light chain M7 experimental SAS data
MODELLER model
Sample: Immunoglobulin light chain M7 dimer, 46 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 May 12
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.5 nm
Dmax 8.0 nm
VolumePorod 58 nm3

SASDVQ4 – Immunoglobulin light chain M10

Immunoglobulin light chain M10 experimental SAS data
ALPHAFOLD model
Sample: Immunoglobulin light chain M10 dimer, 45 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Mar 17
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.6 nm
Dmax 8.3 nm
VolumePorod 58 nm3

SASDTK7 – RECQ like helicase 5 (1 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Mar 29
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 6.5 nm
Dmax 19.5 nm
VolumePorod 310 nm3

SASDTL7 – RECQ like helicase 5 (4 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Mar 29
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 6.4 nm
Dmax 20.2 nm
VolumePorod 288 nm3

SASDTM7 – RECQ like helicase 5 fragment (amino acids 625-825; 0.2 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 21 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Apr 19
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 3.7 nm
Dmax 9.3 nm
VolumePorod 73 nm3

SASDTN7 – RECQ like helicase 5 fragment (amino acids 625-825; 0.4 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Apr 19
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 3.9 nm
Dmax 10.1 nm
VolumePorod 91 nm3

SASDTP7 – RECQ like helicase 5 fragment (amino acids 625-825; 0.6 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Apr 19
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 4.3 nm
Dmax 11.2 nm
VolumePorod 116 nm3

SASDTQ7 – RECQ like helicase 5 fragment (amino acids 625-825; 0.8 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Apr 19
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 4.6 nm
Dmax 13.2 nm
VolumePorod 102 nm3