Browse by ORGANISM: Homo sapiens (Human)

SASDTR7 – RECQ like helicase 5 fragment (amino acids 625-825; 1.0 mg/ml)

ATP-dependent DNA helicase Q5 experimental SAS data
ATP-dependent DNA helicase Q5 Kratky plot
Sample: ATP-dependent DNA helicase Q5, 109 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Apr 19
Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Tomas Klumpler
RgGuinier 5.7 nm
Dmax 16.2 nm
VolumePorod 150 nm3

SASDVR4 – Endophilin B1 wild type (0.69 mg/ml)

Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 dimer, 82 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 5.1 nm
Dmax 16.0 nm
VolumePorod 151 nm3

SASDVS4 – Endophilin B1 wild type (0.34mg/ml)

Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 dimer, 82 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 5.0 nm
Dmax 16.0 nm
VolumePorod 152 nm3

SASDVT4 – Endophilin B1 wild type (0.14 mg/ml)

Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 monomer, 41 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 3.7 nm
Dmax 15.3 nm
VolumePorod 47 nm3

SASDVU4 – Endophilin B1 truncated construction without SH3 domain

Endophilin-B1 (Δ307-360) experimental SAS data
Sample: Endophilin-B1 (Δ307-360) dimer, 68 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 4.6 nm
Dmax 15.2 nm
VolumePorod 149 nm3

SASDTU8 – Complement C3* at 1.25 mg/mL (pH 6.0, 200 mM NaCl)

Complement C3 (Δ668-671) experimental SAS data
CORAL model
Sample: Complement C3 (Δ668-671) monomer, 187 kDa Homo sapiens protein
Buffer: 20 mM MES pH 6.0, 200 mM NaCl, pH: 6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Nov 7
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring. Nat Struct Mol Biol (2025)
Gadeberg TAF, Jørgensen MH, Olesen HG, Lorentzen J, Harwood SL, Almeida AV, Fruergaard MU, Jensen RK, Kanis P, Pedersen H, Tranchant E, Petersen SV, Thøgersen IB, Kragelund BB, Lyons JA, Enghild JJ, Andersen GR
RgGuinier 5.4 nm
Dmax 21.8 nm
VolumePorod 357 nm3

SASDVY6 – Wild-type full-length Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.9 nm
Dmax 9.2 nm
VolumePorod 56 nm3

SASDVZ6 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) triple mutant I12A/F14A/H20A (AIA-A)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.1 nm
Dmax 10.5 nm
VolumePorod 62 nm3

SASDV27 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant H20D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.2 nm
Dmax 11.2 nm
VolumePorod 66 nm3

SASDV37 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant L28D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.8 nm
Dmax 9.2 nm
VolumePorod 52 nm3