Browse by ORGANISM: Mus musculus (Mouse)

SASDNC6 – Ox40 RNA (untranslated region, UTR), alternative decay element (ADEshort)

Ox40 3 UTR ADEshort experimental SAS data
Ox40 3 UTR ADEshort Kratky plot
Sample: Ox40 3 UTR ADEshort monomer, 7 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Aug 7
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 1.7 nm
Dmax 9.0 nm
VolumePorod 12 nm3

SASDLT2 – 6D11 IgG monoclonal antibody

Anti-prion protein monoclonal IgG2a 6D11 experimental SAS data
CORAL model
Sample: Anti-prion protein monoclonal IgG2a 6D11 monomer, 145 kDa Mus musculus protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 15
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies. Sci Adv 7(48):eabj1826 (2021)
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasini E, Saftig P, Schweizer M, Svergun D, Amin L, Mazzola F, Varani L, Thapa S, Gilch S, Schätzl H, Harris DA, Triller A, Mikhaylova M, Aguzzi A, Altmeppen HC, Glatzel M
RgGuinier 5.1 nm
Dmax 17.4 nm
VolumePorod 330 nm3

SASDLU2 – 2:1 complex between anti prion protein monoclonal IgG 6D11 and recombinant murine prion protein

Major prion proteinAnti-prion protein monoclonal IgG2a 6D11 experimental SAS data
OTHER model
Sample: Major prion protein monomer, 23 kDa Mus musculus protein
Anti-prion protein monoclonal IgG2a 6D11 monomer, 145 kDa Mus musculus protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 15
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies. Sci Adv 7(48):eabj1826 (2021)
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasini E, Saftig P, Schweizer M, Svergun D, Amin L, Mazzola F, Varani L, Thapa S, Gilch S, Schätzl H, Harris DA, Triller A, Mikhaylova M, Aguzzi A, Altmeppen HC, Glatzel M
RgGuinier 8.1 nm
Dmax 24.8 nm
VolumePorod 710 nm3

SASDMN2 – Mouse Kirrel2 ectodomain

Kin of IRRE-like protein 2 experimental SAS data
Kin of IRRE-like protein 2 Kratky plot
Sample: Kin of IRRE-like protein 2 dimer, 106 kDa Mus musculus protein
Buffer: 10 mM HEPES pH 7.2, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 3
Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep 37(5):109940 (2021)
Wang J, Vaddadi N, Pak JS, Park Y, Quilez S, Roman CA, Dumontier E, Thornton JW, Cloutier JF, Özkan E
RgGuinier 8.9 nm
Dmax 39.0 nm

SASDMP2 – Mouse Kirrel3 ectodomain

Kin of IRRE-like protein 3 experimental SAS data
SASREF model
Sample: Kin of IRRE-like protein 3 dimer, 106 kDa Mus musculus protein
Buffer: 10 mM HEPES pH 7.2, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 3
Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep 37(5):109940 (2021)
Wang J, Vaddadi N, Pak JS, Park Y, Quilez S, Roman CA, Dumontier E, Thornton JW, Cloutier JF, Özkan E
RgGuinier 9.3 nm
Dmax 34.5 nm

SASDMQ2 – Mouse Kirrel3 ectodomain - Q128A mutant

Kin of IRRE-like protein 3 (Q128A) experimental SAS data
Mouse Kirrel3 ectodomain - Q128A mutant Rg histogram
Sample: Kin of IRRE-like protein 3 (Q128A) monomer, 53 kDa Mus musculus protein
Buffer: 10 mM HEPES pH 7.2, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 3
Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep 37(5):109940 (2021)
Wang J, Vaddadi N, Pak JS, Park Y, Quilez S, Roman CA, Dumontier E, Thornton JW, Cloutier JF, Özkan E
RgGuinier 5.4 nm
Dmax 21.3 nm

SASDF59 – LIM domain-binding protein 1 (Ldb1) self association domain

LIM domain-binding protein 1 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: LIM domain-binding protein 1 dimer, 45 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Nov 19
Self association of LIM domain binding protein 1, LDB1
Jacqueline Matthews
RgGuinier 2.5 nm
Dmax 8.8 nm
VolumePorod 80 nm3

SASDF69 – LIM domain-binding protein 1 (Ldb1) self association domain L87E

LIM domain-binding protein 1, L87E experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: LIM domain-binding protein 1, L87E dimer, 45 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Nov 19
Self association of LIM domain binding protein 1, LDB1
Jacqueline Matthews
RgGuinier 2.4 nm
Dmax 7.8 nm
VolumePorod 84 nm3

SASDF79 – LIM domain-binding protein 1 (Ldb1) self association domain L87K

LIM domain-binding protein 1, L87K experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: LIM domain-binding protein 1, L87K dimer, 45 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Nov 19
Self association of LIM domain binding protein 1, LDB1
Jacqueline Matthews
RgGuinier 2.4 nm
Dmax 7.6 nm
VolumePorod 78 nm3

SASDF89 – LIM domain-binding protein 1 (Ldb1) self association domain L87Q

LIM domain-binding protein 1, L87Q experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: LIM domain-binding protein 1, L87Q dimer, 45 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Nov 19
Self association of LIM domain binding protein 1, LDB1
Jacqueline Matthews
RgGuinier 2.4 nm
Dmax 7.4 nm
VolumePorod 82 nm3