SASDJR7 – Mouse cysteine sulphinic acid decarboxylase (CSAD)

Cysteine sulfinic acid decarboxylase experimental SAS data
SREFLEX model
Sample: Cysteine sulfinic acid decarboxylase dimer, 117 kDa Mus musculus protein
Buffer: 20 mM HEPES, 200 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2018 Feb 4
Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase. J Struct Biol :107674 (2020)
Mahootchi E, Raasakka A, Luan W, Muruganandam G, Loris R, Haavik J, Kursula P
RgGuinier 3.4 nm
Dmax 15.0 nm
VolumePorod 198 nm3

SASDJY7 – A modular diphtheria toxin/flavohemoprotein nanotransporter (MNT) fused to a melanocyte stimulating hormone ligand module (MNT-MSH)

Modular nanotransporter with a melanocyte stimulating hormone ligand module experimental SAS data
A modular diphtheria toxin/flavohemoprotein nanotransporter (MNT) fused to a melanocyte stimulating hormone ligand module (MNT-MSH) Rg histogram
Sample: Modular nanotransporter with a melanocyte stimulating hormone ligand module monomer, 70 kDa synthetic construct protein
Buffer: 150 mM NaCl, 10 mM phosphate buffer saline, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2016 Nov 24
Low-resolution structures of modular nanotransporters shed light on their functional activity Acta Crystallographica Section D Structural Biology 76(12):1270-1279 (2020)
Khramtsov Y, Vlasova A, Vlasov A, Rosenkranz A, Ulasov A, Ryzhykau Y, Kuklin A, Orekhov A, Eydlin I, Georgiev G, Gordeliy V, Sobolev A
RgGuinier 3.7 nm
Dmax 13.3 nm
VolumePorod 127 nm3

SASDJZ7 – A modular diphtheria toxin/flavohemoprotein nanotransporter (MNT) fused to an epidermal growth factor ligand module (MNT-EGF)

Modular nanotransporter with an epidermal growth factor ligand module experimental SAS data
GASBOR model
Sample: Modular nanotransporter with an epidermal growth factor ligand module monomer, 76 kDa synthetic construct protein
Buffer: 150 mM NaCl, 10 mM phosphate buffer saline, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2016 Nov 24
Low-resolution structures of modular nanotransporters shed light on their functional activity Acta Crystallographica Section D Structural Biology 76(12):1270-1279 (2020)
Khramtsov Y, Vlasova A, Vlasov A, Rosenkranz A, Ulasov A, Ryzhykau Y, Kuklin A, Orekhov A, Eydlin I, Georgiev G, Gordeliy V, Sobolev A
RgGuinier 4.2 nm
Dmax 16.0 nm
VolumePorod 161 nm3

SASDJQ7 – Human Cathepsin X

Cathepsin Z experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Cathepsin Z dimer, 54 kDa Homo sapiens protein
Buffer: 20 mM sodium acetate, 1 mM EDTA, pH: 5.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Dec 6
Human cathepsin X/Z is a biologically active homodimer. Biochim Biophys Acta Proteins Proteom :140567 (2020)
Dolenc I, Štefe I, Turk D, Taler-Verčič A, Turk B, Turk V, Stoka V
RgGuinier 2.6 nm
Dmax 6.5 nm
VolumePorod 89 nm3

SASDJG5 – SARS-CoV-2 Main Protease

3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a dimer, 68 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, 1 mM DTT, 1 mM EDTA, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, University of British Columbia on 2020 Jun 1
Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun 11(1):5877 (2020)
Lee J, Worrall LJ, Vuckovic M, Rosell FI, Gentile F, Ton AT, Caveney NA, Ban F, Cherkasov A, Paetzel M, Strynadka NCJ
RgGuinier 2.7 nm
Dmax 8.8 nm
VolumePorod 93 nm3

SASDJH5 – SARS-CoV-2 Main Protease, P9T mutant

3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a, PT9 mutant experimental SAS data
SREFLEX model
Sample: 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a, PT9 mutant monomer, 34 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, 1 mM DTT, 1 mM EDTA, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, University of British Columbia on 2020 Jun 1
Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun 11(1):5877 (2020)
Lee J, Worrall LJ, Vuckovic M, Rosell FI, Gentile F, Ton AT, Caveney NA, Ban F, Cherkasov A, Paetzel M, Strynadka NCJ
RgGuinier 2.4 nm
Dmax 7.2 nm
VolumePorod 54 nm3

SASDHG6 – N-terminal engineered, disulfide-containing endo-beta-N-acetylglucosaminidase H at 36.3 Gy X-ray dose (J/kg)

Endo-beta-N-acetylglucosaminidase H experimental SAS data
Endo-beta-N-acetylglucosaminidase H Kratky plot
Sample: Endo-beta-N-acetylglucosaminidase H dimer, 61 kDa Streptomyces plicatus protein
Buffer: 20 mM Tris-HCl, 50 mM NaCl, 5 mM EDTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Nov 4
SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique PLOS ONE 15(11):e0239702 (2020)
Stachowski T, Snell M, Snell E, Boggon T
RgGuinier 3.0 nm
VolumePorod 69 nm3

SASDHH6 – N-terminal engineered, disulfide-containing endo-beta-N-acetylglucosaminidase H at 72.6 Gy X-ray dose (J/kg)

Endo-beta-N-acetylglucosaminidase H experimental SAS data
Endo-beta-N-acetylglucosaminidase H Kratky plot
Sample: Endo-beta-N-acetylglucosaminidase H dimer, 61 kDa Streptomyces plicatus protein
Buffer: 20 mM Tris-HCl, 50 mM NaCl, 5 mM EDTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Nov 4
SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique PLOS ONE 15(11):e0239702 (2020)
Stachowski T, Snell M, Snell E, Boggon T
RgGuinier 3.1 nm
VolumePorod 68 nm3

SASDHJ6 – N-terminal engineered, disulfide-containing endo-beta-N-acetylglucosaminidase H at 108.9 Gy X-ray dose (J/kg)

Endo-beta-N-acetylglucosaminidase H experimental SAS data
Endo-beta-N-acetylglucosaminidase H Kratky plot
Sample: Endo-beta-N-acetylglucosaminidase H dimer, 61 kDa Streptomyces plicatus protein
Buffer: 20 mM Tris-HCl, 50 mM NaCl, 5 mM EDTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Nov 4
SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique PLOS ONE 15(11):e0239702 (2020)
Stachowski T, Snell M, Snell E, Boggon T
RgGuinier 3.0 nm
VolumePorod 67 nm3

SASDHK6 – N-terminal engineered, disulfide-containing endo-beta-N-acetylglucosaminidase H at 145.2 Gy X-ray dose (J/kg)

Endo-beta-N-acetylglucosaminidase H experimental SAS data
Endo-beta-N-acetylglucosaminidase H Kratky plot
Sample: Endo-beta-N-acetylglucosaminidase H dimer, 61 kDa Streptomyces plicatus protein
Buffer: 20 mM Tris-HCl, 50 mM NaCl, 5 mM EDTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Nov 4
SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique PLOS ONE 15(11):e0239702 (2020)
Stachowski T, Snell M, Snell E, Boggon T
RgGuinier 3.0 nm
VolumePorod 66 nm3

4780 hits found.