COVID Main Protease

Nathanael Caveney Submitted to SASBDB: 2020 Jul 9
Published in SASBDB:

SASDJG5 – SARS-CoV-2 Main Protease

3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a experimental SAS data
PDB model
Sample: 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a dimer, 68 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, 1 mM DTT, 1 mM EDTA, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, University of British Columbia on 2020 Jun 1
RgGuinier 2.7 nm
Dmax 8.8 nm
VolumePorod 93 nm3

SASDJH5 – SARS-CoV-2 Main Protease, P9T mutant

3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a, PT9 mutant experimental SAS data
SREFLEX model
Sample: 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a, PT9 mutant monomer, 34 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, 1 mM DTT, 1 mM EDTA, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, University of British Columbia on 2020 Jun 1
RgGuinier 2.4 nm
Dmax 7.2 nm
VolumePorod 54 nm3