Structural flexibility of the tetanus neurotoxin revealed by crystallographic and solution scattering analyses.

Zhang CM, Imoto Y, Hikima T, Inoue T
J Struct Biol X 5:100045 (2021)
PMID: 33598655
doi: 10.1016/j.yjsbx.2021.100045
Submitted to SASBDB: 2020 Jul 20
Published in SASBDB:

SASDJN5 – Isolated translocation domain of tetanus nerotoxin (TeNT/iHn)

Tetanus toxin (C467S) experimental SAS data
Isolated translocation domain of tetanus nerotoxin (TeNT/iHn) Rg histogram
Sample: Tetanus toxin (C467S) monomer, 46 kDa Clostridium tetani protein
Buffer: 10 mM HEPES 100 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BL45XU, SPring-8 on 2018 Oct 20
RgGuinier 3.0 nm
Dmax 12.1 nm
VolumePorod 54 nm3

SASDJP5 – Beltless isolated translocation domain of tetanus nerotoxin (TeNT/blHn)

Tetanus toxin experimental SAS data
PDB model
Sample: Tetanus toxin monomer, 35 kDa Clostridium tetani protein
Buffer: 10 mM HEPES 100 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BL45XU, SPring-8 on 2018 Oct 20
RgGuinier 2.9 nm
Dmax 11.3 nm
VolumePorod 42 nm3