A cocrystal structure of dengue capsid protein in complex of inhibitor.

Xia H, Xie X, Zou J, Noble CG, Russell WK, Holthauzen LMF, Choi KH, White MA, Shi PY
Proc Natl Acad Sci U S A 117(30):17992-18001 (2020 Jul 28)
PMID: 32669438
doi: 10.1073/pnas.2003056117
Submitted to SASBDB: 2019 Dec 12
Published in SASBDB:

SASDHJ4 – Dengue Virus 2 New Guinea C (DENV-2 C, capsid protein), apo form

Dengue Virus 2 New Guinea C experimental SAS data
CORAL model
Sample: Dengue Virus 2 New Guinea C dimer, 19 kDa Dengue virus 2 protein
Buffer: 100 mM NaCl, 25 mM HEPES, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-1000, Sealy Center For Structural Biology, UTMB-G on 2018 Jul 5
RgGuinier 1.8 nm
Dmax 5.4 nm
VolumePorod 52 nm3

SASDHK4 – Dengue Virus 2 New Guinea C (DENV-2 C, capsid protein) with saturating ST148 inhibitor

Dengue Virus 2 New Guinea C experimental SAS data
CORAL model
Sample: Dengue Virus 2 New Guinea C dimer, 19 kDa Dengue virus 2 protein
Buffer: 100 mM NaCl, 25 mM HEPES, pH 7.4, 10 ┬ÁM ST148, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-1000, Sealy Center For Structural Biology, UTMB-G on 2018 Jul 26
RgGuinier 1.9 nm
Dmax 6.0 nm
VolumePorod 52 nm3