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14 hits found for Bao Nguyen Viet

SASDXJ5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit alpha holoenzyme with Exon 14 as the linker region

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) dodecamer, 620 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 8.1 nm

SASDXK5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 14 as the linker region + 10 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) dodecamer, 620 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.5 nm

SASDXL5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 14 as the linker region + 2000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) dodecamer, 620 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 8.4 nm

SASDXM5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 14 as the linker region + 20000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) dodecamer, 620 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 9.9 nm

SASDXN5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 6.9 nm

SASDXP5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 10 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.1 nm

SASDXQ5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 100 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.2 nm

SASDXR5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 1000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.6 nm

SASDXS5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 2000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.2 nm

SASDXT5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 5000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.8 nm

SASDXU5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 10000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 8.0 nm

SASDXV5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 20000 nM Ca2+/CaM

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 10.0 nm

SASDVU7 – Ca2+/calmodulin-dependent protein kinase II (CaMKII) holoenzyme with Exon 14 as the linker region

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
GASBOR model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) dodecamer, 620 kDa Homo sapiens protein
Buffer: 25 mM tris-HCl pH 8.8, 250 mM KCl, 1 mM TCEP, 2% glycerol, pH:
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Apr 17
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. Nat Commun 16(1):8461 (2025)
Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM
RgGuinier 6.8 nm
Dmax 25.7 nm
VolumePorod 1437 nm3

SASDVV7 – Ca2+/calmodulin-dependent protein kinase II (CaMKII) holoenzyme with Exon 18 as the linker region

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
GASBOR model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 25 mM tris-HCl pH 8.8, 250 mM KCl, 1 mM TCEP, 2% glycerol, pH:
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Apr 17
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. Nat Commun 16(1):8461 (2025)
Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM
RgGuinier 6.0 nm
Dmax 19.0 nm
VolumePorod 1080 nm3