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18
hits found for
Karthikeyan Dhamotharan
SASDR83
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA Stem loop 2 and 3 of SARS-CoV-2 in HEPES conditions
Sample:
Stem loop 2 and 3 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Nucleoprotein dimer, 30 kDa
Severe acute respiratory …
protein
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements
Karthikeyan
Dhamotharan
R
g
Guinier
2.9
nm
D
max
10.5
nm
Volume
Porod
69
nm
3
SASDR93
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA Stem loop 4 with AU extension of SARS-CoV-2 in HEPES conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Stem loop 4 with AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 22 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements
Karthikeyan
Dhamotharan
R
g
Guinier
3.2
nm
D
max
11.8
nm
Volume
Porod
50
nm
3
SASDRA3
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA AU extension of SARS-CoV-2 in HEPES conditions
Sample:
AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 7 kDa
Severe acute respiratory …
RNA
Nucleoprotein dimer, 30 kDa
Severe acute respiratory …
protein
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements
Karthikeyan
Dhamotharan
R
g
Guinier
2.6
nm
D
max
9.0
nm
Volume
Porod
46
nm
3
SASDRB3
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA Stem loop 4 of SARS-CoV-2 in HEPES conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Stem loop 4 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements
Karthikeyan
Dhamotharan
R
g
Guinier
2.7
nm
D
max
10.0
nm
Volume
Porod
46
nm
3
SASDPK6
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) of SARS-CoV-2 in phosphate conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Aug 16
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
1.6
nm
D
max
6.1
nm
Volume
Porod
23
nm
3
SASDPL6
– 5'-genomic RNA Stem loop 2 and 3 of SARS-CoV-2 in phosphate conditions
Sample:
Stem loop 2 and 3 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Nov 22
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.2
nm
D
max
8.0
nm
Volume
Porod
24
nm
3
SASDPM6
– 5'-genomic RNA Stem loop 4 of SARS-CoV-2 in phosphate conditions
Sample:
Stem loop 4 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Nov 22
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.0
nm
D
max
7.1
nm
Volume
Porod
22
nm
3
SASDPN6
– 5'-genomic RNA Stem loop 4 with AU extension of SARS-CoV-2 in phosphate conditions
Sample:
Stem loop 4 with AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 22 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Nov 22
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.8
nm
D
max
10.2
nm
Volume
Porod
33
nm
3
SASDPP6
– 5'-genomic RNA AU extension of SARS-CoV-2 in phosphate conditions
Sample:
AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 7 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Nov 22
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
1.5
nm
D
max
5.4
nm
Volume
Porod
13
nm
3
SASDPQ6
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA Stem loop 2 and 3 of SARS-CoV-2 in phosphate conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Stem loop 2 and 3 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Aug 16
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.4
nm
D
max
9.0
nm
Volume
Porod
38
nm
3
SASDPR6
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA Stem loop 4 with AU extension of SARS-CoV-2 in phosphate conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Stem loop 4 with AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 22 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Aug 16
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
3.4
nm
D
max
13.5
nm
Volume
Porod
51
nm
3
SASDPS6
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) complexed with 5'-genomic RNA AU extension of SARS-CoV-2 in phosphate conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 7 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Aug 16
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.1
nm
D
max
8.5
nm
Volume
Porod
32
nm
3
SASDPT6
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) with 5'-genomic RNA Stem loop 4 of SARS-CoV-2 in phosphate conditions (mixture)
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Stem loop 4 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM potassium phosphate, 150 mM KCl, 2 mM TCEP, pH: 6.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2021 Nov 22
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.1
nm
D
max
7.8
nm
Volume
Porod
25
nm
3
SASDR33
– N-terminal RNA-binding domain (NTD) of nucleocapsid protein (N) of SARS-CoV-2 in HEPES conditions
Sample:
Nucleoprotein monomer, 15 kDa
Severe acute respiratory …
protein
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
1.6
nm
D
max
5.2
nm
Volume
Porod
26
nm
3
SASDR43
– 5'-genomic RNA Stem loop 2 and 3 of SARS-CoV-2 in HEPES conditions
Sample:
Stem loop 2 and 3 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.3
nm
D
max
9.5
nm
Volume
Porod
28
nm
3
SASDR53
– 5'-genomic RNA Stem loop 4 of SARS-CoV-2 in HEPES conditions
Sample:
Stem loop 4 in the 5'-genomic end of SARS-CoV-2 monomer, 14 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
2.1
nm
D
max
7.7
nm
Volume
Porod
22
nm
3
SASDR63
– 5'-genomic RNA Stem loop 4 with AU extension of SARS-CoV-2 in HEPES conditions
Sample:
Stem loop 4 with AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 22 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
3.1
nm
D
max
11.7
nm
Volume
Porod
35
nm
3
SASDR73
– 5'-genomic RNA AU extension of SARS-CoV-2 in HEPES conditions
Sample:
AU extension in the 5'-genomic end of SARS-CoV-2 monomer, 7 kDa
Severe acute respiratory …
RNA
Buffer:
25 mM HEPES, 75 mM KCl, 2.5 mM NaNO3, pH: 7.2
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2022 Nov 29
The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.
Nat Commun
14(1):3331 (2023)
...
Dhamotharan
K, Jeffries CM, Schlundt A
R
g
Guinier
1.7
nm
D
max
7.0
nm
Volume
Porod
13
nm
3