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6 hits found for Kerr

SASDVC9 – 7SK small nuclear RNA State A Low Magnesium Concentration Ensemble

RNA component of 7SK nuclear ribonucleoprotein experimental SAS data
DAMMIN model
Sample: RNA component of 7SK nuclear ribonucleoprotein monomer, 107 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
...Kerr L, Girodat D, Patel T
RgGuinier 8.0 nm
Dmax 23.2 nm
VolumePorod 600 nm3

SASDVD9 – 7SK small nuclear RNA State B Low Magnesium Concentration Ensemble

RNA component of 7SK nuclear ribonucleoprotein experimental SAS data
DAMMIN model
Sample: RNA component of 7SK nuclear ribonucleoprotein monomer, 107 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
...Kerr L, Girodat D, Patel T
RgGuinier 7.9 nm
Dmax 24.1 nm
VolumePorod 290 nm3

SASDVE9 – 7SL Signal Recognition Particle

7SL Signal Reocgnition Particle RNA experimental SAS data
DAMMIN model
Sample: 7SL Signal Reocgnition Particle RNA monomer, 98 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
...Kerr L, Girodat D, Patel T
RgGuinier 6.7 nm
Dmax 21.7 nm
VolumePorod 300 nm3

SASDBP9 – Human Hsp90 co-chaperone Cdc37 protein (CD37)

Hsp90 co-chaperone Cdc37 experimental SAS data
CORAL model
Sample: Hsp90 co-chaperone Cdc37 monomer, 44 kDa Homo sapiens protein
Buffer: 25 mM Tris.Cl, 150 mM NaCl, 5% (v/v) glycerol, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 10
Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System. Structure 26(3):446-458.e8 (2018)
...Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M
RgGuinier 4.0 nm
Dmax 15.5 nm
VolumePorod 106 nm3

SASDBQ9 – Human Hsp90 co-chaperone Cdc37 (CD37) in complex with fibroblast growth factor receptor 3

Hsp90 co-chaperone Cdc37Fibroblast growth factor receptor 3 experimental SAS data
CORAL model
Sample: Hsp90 co-chaperone Cdc37 monomer, 44 kDa Homo sapiens protein
Fibroblast growth factor receptor 3 monomer, 35 kDa Homo sapiens protein
Buffer: 25 mM Tris.Cl, 150 mM NaCl, 5% (v/v) glycerol, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 10
Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System. Structure 26(3):446-458.e8 (2018)
...Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M
RgGuinier 4.7 nm
Dmax 19.5 nm
VolumePorod 161 nm3

SASDBR9 – Human fibroblast growth factor receptor 3, from SEC-SAXS

Fibroblast growth factor receptor 3 experimental SAS data
CORAL model
Sample: Fibroblast growth factor receptor 3 monomer, 35 kDa Homo sapiens protein
Buffer: 25 mM Tris.Cl, 150 mM NaCl, 5% (v/v) glycerol, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 10
Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System. Structure 26(3):446-458.e8 (2018)
...Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M
RgGuinier 2.4 nm
Dmax 8.3 nm
VolumePorod 59 nm3