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3 hits found for Neri

SASDJN8 – L19-IL2 dimeric immunocytokine

L19-IL2 dimeric immunocytokine experimental SAS data
ALLOSMOD model
Sample: L19-IL2 dimeric immunocytokine dimer, 84 kDa synthetic construct protein
Buffer: 25 mM HEPES/NaOH, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2018 Jan 23
Inference of molecular structure for characterization and improvement of clinical grade immunocytokines Journal of Structural Biology :107696 (2021)
...Neri D, Villa A, Forneris F
RgGuinier 4.1 nm
Dmax 11.9 nm
VolumePorod 128 nm3

SASDJP8 – L19L19-IL2 immunocytokine monomer

L19L19-IL2 immunocytokine experimental SAS data
GASBOR model
Sample: L19L19-IL2 immunocytokine monomer, 69 kDa synthetic construct protein
Buffer: 25 mM HEPES/NaOH, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Mar 4
Inference of molecular structure for characterization and improvement of clinical grade immunocytokines Journal of Structural Biology :107696 (2021)
...Neri D, Villa A, Forneris F
RgGuinier 3.6 nm
Dmax 10.8 nm
VolumePorod 93 nm3

SASDJQ8 – IL12-L19L19 immunocytokine monomer

IL12-L19L19 immunocytokine experimental SAS data
GASBOR model
Sample: IL12-L19L19 immunocytokine monomer, 112 kDa synthetic construct protein
Buffer: 25 mM HEPES/NaOH, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Mar 4
Inference of molecular structure for characterization and improvement of clinical grade immunocytokines Journal of Structural Biology :107696 (2021)
...Neri D, Villa A, Forneris F
RgGuinier 4.5 nm
Dmax 14.2 nm
VolumePorod 224 nm3