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14
hits found for
Panjkovich
SASDTG2
– LCP domain of LytR from Streptococcus dysgalactiae in the presence of geranylgeranyl diphosphate (150 mM NaCl)
Sample:
Biofilm regulatory protein monomer, 34 kDa
Streptococcus dysgalactiae subsp. …
protein
Buffer:
50 mM HEPES, 150 mM NaCl, 5 mM MgCl2, pH: 8
Experiment:
SAXS data collected at BM29, ESRF
on 2022 Jun 1
Structural insights of an LCP protein-LytR-from Streptococcus dysgalactiae subs. dysgalactiae through biophysical and in silico methods.
Front Chem
12:1379914 (2024)
...
Panjkovich
A, Svergun D, Santos MFA, Correia MAS, Fernandes AR, Romão MJ, Sousa SF, Santos-Silva T
R
g
Guinier
2.5
nm
D
max
8.0
nm
Volume
Porod
83
nm
3
SASDTH2
– LCP domain of LytR from Streptococcus dysgalactiae in the absence of ligand (150 mM NaCl)
Sample:
Biofilm regulatory protein monomer, 34 kDa
Streptococcus dysgalactiae subsp. …
protein
Buffer:
50 mM HEPES, 150 mM NaCl, 5 mM MgCl2, pH: 8
Experiment:
SAXS data collected at BM29, ESRF
on 2022 Jun 1
Structural insights of an LCP protein-LytR-from Streptococcus dysgalactiae subs. dysgalactiae through biophysical and in silico methods.
Front Chem
12:1379914 (2024)
...
Panjkovich
A, Svergun D, Santos MFA, Correia MAS, Fernandes AR, Romão MJ, Sousa SF, Santos-Silva T
R
g
Guinier
2.4
nm
D
max
9.0
nm
Volume
Porod
76
nm
3
SASDF53
– Bruton's Tyrosine Kinase - kinase domain
Sample:
Bruton's tyrosine kinase, kinase domain monomer, 32 kDa
Homo sapiens
protein
Buffer:
20mM Tris, 150mM NaCl, 1mM TCEP, 5% glycerol, pH: 7.5
Experiment:
SAXS data collected at BM29, ESRF
on 2018 May 11
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Nature Communications
11(1) (2020)
...
Panjkovich
A, Georgeon S, Kükenshöner T, Marcaida M, Pojer F, De Vivo M, Svergun D, Kim H, Dal Peraro M, Hantschel O
R
g
Guinier
2.1
nm
D
max
6.8
nm
Volume
Porod
52
nm
3
SASDF63
– Bruton's Tyrosine Kinase - SH2-kinase domain
Sample:
Bruton's tyrosine kinase - Src homolgy domain 2 - kinase domain monomer, 46 kDa
Homo sapiens
protein
Buffer:
20mM Tris, 150mM NaCl, 1mM TCEP, 5% glycerol, pH: 7.5
Experiment:
SAXS data collected at BM29, ESRF
on 2018 Nov 3
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Nature Communications
11(1) (2020)
...
Panjkovich
A, Georgeon S, Kükenshöner T, Marcaida M, Pojer F, De Vivo M, Svergun D, Kim H, Dal Peraro M, Hantschel O
R
g
Guinier
2.8
nm
D
max
9.4
nm
Volume
Porod
64
nm
3
SASDF73
– Bruton's Tyrosine Kinase - SH3-SH2-kinase domain
Sample:
Bruton's tyrosine kinase - Src homology 3-2 kinase domain monomer, 52 kDa
Homo sapiens
protein
Buffer:
20mM Tris, 150mM NaCl, 1mM TCEP, 5% glycerol, pH: 7.5
Experiment:
SAXS data collected at BM29, ESRF
on 2018 Nov 2
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Nature Communications
11(1) (2020)
...
Panjkovich
A, Georgeon S, Kükenshöner T, Marcaida M, Pojer F, De Vivo M, Svergun D, Kim H, Dal Peraro M, Hantschel O
R
g
Guinier
2.6
nm
D
max
8.3
nm
Volume
Porod
72
nm
3
SASDF83
– Bruton's Tyrosine Kinase - Full-length
Sample:
Bruton's tyrosine kinase - full length monomer, 77 kDa
Homo sapiens
protein
Buffer:
20mM Tris, 150mM NaCl, 1mM TCEP, 5% glycerol, pH: 7.5
Experiment:
SAXS data collected at BM29, ESRF
on 2018 Nov 3
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Nature Communications
11(1) (2020)
...
Panjkovich
A, Georgeon S, Kükenshöner T, Marcaida M, Pojer F, De Vivo M, Svergun D, Kim H, Dal Peraro M, Hantschel O
R
g
Guinier
4.0
nm
D
max
15.6
nm
Volume
Porod
114
nm
3
SASDC26
– DH-PH - Dbl-homology domain (DH) and Pleckstrin-homology (PH) of Bcr-Abl tyrosine kinase p210
Sample:
BCR-ABL p210 fusion protein (DH-PH) monomer, 47 kDa
Homo sapiens
protein
Buffer:
25 mM Tris-HCl, 150 mM NaCl, 5% Glycerol, 1 mM DTT, pH: 7.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2015 Oct 13
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
Nat Commun
8(1):2101 (2017)
...
Panjkovich
A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O
R
g
Guinier
3.2
nm
D
max
11.1
nm
Volume
Porod
69
nm
3
SASDC36
– DH - Dbl-homology domain of Bcr-Abl tyrosine kinase p210
Sample:
BCR-ABL p210 fusion protein monomer, 25 kDa
Homo sapiens
protein
Buffer:
25 mM Tris-HCl, 150 mM NaCl, 5% Glycerol, 1 mM DTT, pH: 7.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2015 Oct 13
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
Nat Commun
8(1):2101 (2017)
...
Panjkovich
A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O
R
g
Guinier
2.1
nm
D
max
7.3
nm
Volume
Porod
38
nm
3
SASDC46
– PH - Pleckstrin-homology domain of Bcr-Abl tyrosine kinase p210
Sample:
BCR-ABL p210 fusion protein (PH domain) monomer, 22 kDa
Homo sapiens
protein
Buffer:
25 mM Tris-HCl, 150 mM NaCl, 5% Glycerol, 1 mM DTT, pH: 7.5
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2016 Nov 10
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
Nat Commun
8(1):2101 (2017)
...
Panjkovich
A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O
R
g
Guinier
2.0
nm
D
max
6.6
nm
Volume
Porod
38
nm
3
SASDBD9
– ABC transporter periplasmic substrate-binding protein TupA measured in the absence of metal ligand (tungstate or molybdate)
Sample:
ABC transporter periplasmic substrate-binding protein monomer, 30 kDa
Desulfovibrio alaskensis
protein
Buffer:
5 mM Tris-HCl, pH: 7.6
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2013 Dec 7
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
Sci Rep
7(1):5798 (2017)
...
Panjkovich
A, Svergun DI, Santos-Silva T, Rivas MG
R
g
Guinier
2.4
nm
D
max
9.6
nm
Volume
Porod
51
nm
3
SASDBE9
– ABC transporter periplasmic substrate-binding protein TupA measured in the absence of metal ligand (tungstate or molybdate)
Sample:
ABC transporter periplasmic substrate-binding protein monomer, 30 kDa
Desulfovibrio alaskensis
protein
Buffer:
5 mM Tris-HCl, pH: 7.6
Experiment:
SAXS data collected at BM29, ESRF
on 2014 Jun 21
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
Sci Rep
7(1):5798 (2017)
...
Panjkovich
A, Svergun DI, Santos-Silva T, Rivas MG
R
g
Guinier
2.4
nm
D
max
9.5
nm
Volume
Porod
49
nm
3
SASDBF9
– ABC transporter periplasmic substrate-binding protein TupA measured in the presence of tungstate
Sample:
ABC transporter periplasmic substrate-binding protein monomer, 30 kDa
Desulfovibrio alaskensis
protein
Buffer:
5 mM Tris-HCl, pH: 7.6
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2013 Dec 7
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
Sci Rep
7(1):5798 (2017)
...
Panjkovich
A, Svergun DI, Santos-Silva T, Rivas MG
R
g
Guinier
2.3
nm
D
max
9.0
nm
Volume
Porod
46
nm
3
SASDBG9
– ABC transporter periplasmic substrate-binding protein TupA measured in the presence of tungstate
Sample:
ABC transporter periplasmic substrate-binding protein monomer, 30 kDa
Desulfovibrio alaskensis
protein
Buffer:
5 mM Tris-HCl, pH: 7.6
Experiment:
SAXS data collected at BM29, ESRF
on 2014 Jun 21
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
Sci Rep
7(1):5798 (2017)
...
Panjkovich
A, Svergun DI, Santos-Silva T, Rivas MG
R
g
Guinier
2.3
nm
D
max
8.9
nm
Volume
Porod
44
nm
3
SASDBH9
– ABC transporter periplasmic substrate-binding protein TupA measured in the presence of molybdate
Sample:
ABC transporter periplasmic substrate-binding protein monomer, 30 kDa
Desulfovibrio alaskensis
protein
Buffer:
5 mM Tris-HCl, pH: 7.6
Experiment:
SAXS data collected at EMBL P12, PETRA III
on 2013 Dec 7
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
Sci Rep
7(1):5798 (2017)
...
Panjkovich
A, Svergun DI, Santos-Silva T, Rivas MG
R
g
Guinier
2.3
nm
D
max
9.2
nm
Volume
Porod
46
nm
3
