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2 hits found for Aspergillus fumigatus poly(ADP-ribose)polymerase 1

SASDXE9 – poly(ADP-ribose)polymerase 1 (Af-PARP1) apo protein

Aspergillus fumigatus poly(ADP-ribose)polymerase 1 experimental SAS data
Aspergillus fumigatus poly(ADP-ribose)polymerase 1 Kratky plot
Sample: Aspergillus fumigatus poly(ADP-ribose)polymerase 1 monomer, 74 kDa Aspergillus fumigatus protein
Buffer: ...150 mM NaCl, 2 mM TCEP, 2.5% (v/v) Glycerol, pH: 7.5
Experiment: SAXS data collected at ...1, Diamond Light Source on ...14
The BRCT domain enhances DNA binding and catalytic efficiency of fungal PARPs. Nat Commun 17(1) (2026)
Bainbridge AG, Gianga TM, Hussain R, Parkin C, Longhurst AD, Helmstetter N, Farrer RA, Catania S, Siligardi G, Rack JGM
RgGuinier 4.4 nm
Dmax 13.7 nm
VolumePorod 131 nm3

SASDXG9 – poly(ADP-ribose)polymerase 1 (Af-PARP1) 5'P nicked DNA complex

Aspergillus fumigatus poly(ADP-ribose)polymerase 15'Phosphorylated nicked DNA damage mimetic experimental SAS data
Aspergillus fumigatus poly(ADP-ribose)polymerase 1 5'Phosphorylated nicked DNA damage mimetic Kratky plot
Sample: Aspergillus fumigatus poly(ADP-ribose)polymerase 1 monomer, 74 kDa Aspergillus fumigatus protein
5'Phosphorylated nicked DNA damage mimetic monomer, 14 kDa DNA
Buffer: ...150 mM NaCl, 2 mM TCEP, 2.5% (v/v) Glycerol, pH: 7.5
Experiment: SAXS data collected at ...1, Diamond Light Source on ...14
The BRCT domain enhances DNA binding and catalytic efficiency of fungal PARPs. Nat Commun 17(1) (2026)
Bainbridge AG, Gianga TM, Hussain R, Parkin C, Longhurst AD, Helmstetter N, Farrer RA, Catania S, Siligardi G, Rack JGM
RgGuinier 4.3 nm
Dmax 16.6 nm
VolumePorod 190 nm3