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5 hits found for BRME1

SASDSM7 – Full-length Heat shock factor 2-binding protein (HSF2BP)

Heat shock factor 2-binding protein experimental SAS data
Heat shock factor 2-binding protein Kratky plot
Sample: Heat shock factor 2-binding protein tetramer, 150 kDa Homo sapiens protein
Buffer: 25 mM Tris-HCl pH 7.5, 250 mM NaCl, and 5 mM β-mercaptoethanol, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2020 Oct 2
...BRME1 promotes homologous recombination. Sci Adv 9(43):eadi7352 (2023)
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter JM, Ropars V, David G, Arteni AA, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S
RgGuinier 8.5 nm
Dmax 25.0 nm
VolumePorod 364 nm3

SASDH99 – ...BRME1 - MEILB2a1+2-BRME1 2:2 complex

BRME1Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: BRME1 dimer, 23 kDa Mus musculus protein
Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
...BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 5.0 nm
Dmax 19.0 nm
VolumePorod 104 nm3

SASDHA9 – Meiotic localizer of BRCA2 - MEILB2a1+2 dimer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
...BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 4.6 nm
Dmax 16.0 nm
VolumePorod 88 nm3

SASDHB9 – Meiotic localizer of BRCA2 - MEILB2a1+2 octamer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 octamer, 102 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
...BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 5.7 nm
Dmax 20.0 nm
VolumePorod 368 nm3

SASDHC9 – Meiotic localizer of BRCA2 - MEILB1a2 monomer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 monomer, 9 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
...BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 3.0 nm
Dmax 11.0 nm
VolumePorod 43 nm3