35 hits found for Breast cancer type 2 susceptibility protein (BRC repeat 2)

SASDX95 – ...protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 1 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.5 nm Dmax 28.5 nm VolumePorod 334 nm3

SASDXA5 – ...protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 2 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.5 nm Dmax 28.5 nm VolumePorod 473 nm3

SASDXB5 – ...protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 3.5 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein Buffer: 20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol, pH: 7.5 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 4 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.9 nm Dmax 28.5 nm VolumePorod 652 nm3

SASDXC5 – ...protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 7 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein Buffer: 20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol, pH: 7.5 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 4 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.8 nm Dmax 28.3 nm VolumePorod 542 nm3

SASDWT5 – ...repeat (BRC4) SEC-SAXS Sample: Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein ...protein RAD51 homolog 1 (Δ97) monomer, 26 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 May 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.0 nm Dmax 6.6 nm VolumePorod 57 nm3

SASDWU5 – ...repeat (BRC4) at 1 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein ...protein RAD51 homolog 1 (Δ97) monomer, 26 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.0 nm Dmax 6.3 nm VolumePorod 51 nm3

SASDWV5 – ...repeat (BRC4) at 2 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein ...protein RAD51 homolog 1 (Δ97) monomer, 26 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.1 nm Dmax 6.6 nm VolumePorod 49 nm3

SASDWW5 – ...repeat (BRC4) at 4 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein ...protein RAD51 homolog 1 (Δ97) monomer, 26 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.1 nm Dmax 6.3 nm VolumePorod 57 nm3

SASDWX5 – ...repeat (BRC4) at 6 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein ...protein RAD51 homolog 1 (Δ97) monomer, 26 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.1 nm Dmax 6.6 nm VolumePorod 63 nm3

SASDWY5 – ...repeat (BRC4) SEC-SAXS Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 May 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.8 nm Dmax 10.5 nm VolumePorod 74 nm3

SASDWZ5 – ...repeat (BRC4) at 0.5 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.8 nm Dmax 11.0 nm VolumePorod 67 nm3

...26 – ...repeat (BRC4) at 1 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.7 nm Dmax 10.0 nm VolumePorod 64 nm3

SASDW36 – ...repeat (BRC4) at 2 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.7 nm Dmax 10.3 nm VolumePorod 66 nm3

SASDW46 – ...repeat (BRC4) at 4 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 4) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.8 nm Dmax 10.0 nm VolumePorod 72 nm3

SASDW56 – ...repeat (BRC2) SEC-SAXS Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 2) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 May 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.7 nm Dmax 9.6 nm VolumePorod 67 nm3

SASDW66 – ...repeat (BRC2) at 0.5 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 2) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.6 nm Dmax 9.5 nm VolumePorod 83 nm3

SASDW76 – ...repeat (BRC2) at 1 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 2) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.7 nm Dmax 9.6 nm VolumePorod 63 nm3

SASDW86 – ...repeat (BRC2) at 2 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) monomer, 37 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeat 2) monomer, 4 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 2.7 nm Dmax 9.8 nm VolumePorod 69 nm3

SASDW96 – ...2 truncation containing the second and the third BRC repeats (BRC2-3) SEC-SAXS Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 2-3) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.5 nm Dmax 23.0 nm VolumePorod 167 nm3

SASDWA6 – ...2 truncation containing the second and the third BRC repeats (BRC2-3) at 0.5 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 2-3) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.0 nm Dmax 21.0 nm VolumePorod 236 nm3

SASDWB6 – ...2 truncation containing the second and the third BRC repeats (BRC2-3) at 1 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 2-3) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.7 nm Dmax 23.0 nm VolumePorod 225 nm3

SASDWC6 – ...2 truncation containing the second and the third BRC repeats (BRC2-3) at 2 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 2-3) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.7 nm Dmax 22.0 nm VolumePorod 167 nm3

SASDWD6 – ...2 truncation containing the second, third and fourth BRC repeats (BRC2-4) SEC-SAXS Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 6.7 nm Dmax 28.0 nm VolumePorod 259 nm3

SASDWE6 – ...2 truncation containing the third and fourth BRC repeats (BRC3-4) SEC-SAXS Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 May 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 4.6 nm Dmax 18.0 nm VolumePorod 142 nm3

SASDWF6 – ...2 truncation containing the third and fourth BRC repeats (BRC3-4) at 0.5 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 4.6 nm Dmax 18.5 nm VolumePorod 175 nm3

SASDWG6 – ...2 truncation containing the third and fourth BRC repeats (BRC3-4) at 1 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 4.5 nm Dmax 18.0 nm VolumePorod 140 nm3

SASDWH6 – ...2 truncation containing the third and fourth BRC repeats (BRC3-4) at 2 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 4.6 nm Dmax 18.3 nm VolumePorod 148 nm3

SASDWJ6 – ...2 truncation containing the first and the second BRC repeats (BRC1-2) SEC-SAXS Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 May 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.3 nm Dmax 21.0 nm VolumePorod 165 nm3

SASDWK6 – ...2 truncation containing the first and the second BRC repeats (BRC1-2) at 0.5 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.7 nm Dmax 24.0 nm VolumePorod 249 nm3

SASDWL6 – ...2 truncation containing the first and the second BRC repeats (BRC1-2) at 1 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.5 nm Dmax 21.0 nm VolumePorod 208 nm3

SASDWM6 – ...2 truncation containing the first and the second BRC repeats (BRC1-2) at 2 mg/mL Sample: ...protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Jul 1 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 5.5 nm Dmax 23.0 nm VolumePorod 191 nm3

SASDWN6 – ...2 truncation containing the first, second, third and fourth BRC repeats (BRC1-4) SEC-SAXS Sample: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) monomer, 62 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) tetramer, 148 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 7.7 nm Dmax 34.0 nm VolumePorod 409 nm3

SASDWP6 – ...2 truncation containing the first, second, third and fourth BRC repeats (BRC1-4) at 0.5 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) monomer, 62 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) tetramer, 148 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 8.1 nm Dmax 33.0 nm VolumePorod 422 nm3

SASDWQ6 – ...2 truncation containing the first, second, third and fourth BRC repeats (BRC1-4) at 0.98 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) monomer, 62 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) tetramer, 148 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 7.6 nm Dmax 33.3 nm VolumePorod 392 nm3

SASDWR6 – ...2 truncation containing the first, second, third and fourth BRC repeats (BRC1-4) at 2 mg/mL Sample: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) monomer, 62 kDa Homo sapiens protein ...protein RAD51 homolog 1 (F86E A89E) tetramer, 148 kDa Homo sapiens protein Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8 Experiment: SAXS data collected at ...21, Diamond Light Source on 2024 Dec 2 ...repeats interplay in Homologous Recombination (2025) Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A RgGuinier 7.7 nm Dmax 33.0 nm VolumePorod 417 nm3